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Kaletra

Rx: Only available by prescription
Brand Name Kaletra Options
- Manufacturer:
Abbott
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Generic Lopinavir/Ritonavir Options - Manufacturer: Generic
Quantity:
What are Generics? A generic
drug is a copy of the brand-name drug with the same dosage, safety, strength, quality,
how it is taken, performance, and intended use. Before generics become available
on the market, the generic company must prove it has the same active ingredients
as the brand-name and works the same way in the body in the same amount of time.
The only differences between generics and their brand-name counterparts is the generics
are less expensive and may look slightly different (e.g. different shape or color),
as trademark laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large
sums of money to invent a drug. When the brand-name patent expires, generic companies
can manufacture a copy of the brand-name drug and sell it at substantial discounts.
Kaletra Description
This combination product contains two medications, lopinavir and ritonavir. This product is used in combination with other medications to help control your HIV infection, thereby improving your quality of life. It also lowers your risk of getting HIV disease complications (e.g., opportunistic infections, cancer). Both lopinavir and ritonavir belong to a class of drugs known as HIV protease inhibitors. The ritonavir in this product helps the lopinavir to stay in your body. This effect builds up the amount of lopinavir in your body, increasing its effectiveness.
Kaletra Directions
Read the Medication Guide and, if available, the Patient Information Leaflet provided by your pharmacist before you start using lopinavir/ritonavir and each time you get a refill. If you have any questions regarding the information, consult your doctor or pharmacist.
Take this product by mouth with or without food, usually once or twice daily or as directed by your doctor. Swallow the tablets whole. Do not crush, break or chew the tablets.
Dosage is based on your medical condition, response to therapy, and any other anti-HIV medications you may be taking.
Taking this product once a day is not recommended if you have previously taken other drugs to treat your HIV infection. Consult your doctor for more details.
If you are taking didanosine in addition to this product, you can take it at the same time as this product, but take them both without food.
It is very important to continue taking this medication (and other anti-HIV medications) exactly as prescribed by your doctor.
This medication works best when the amount of drug in your body is kept at a constant level. Therefore, take this drug at evenly spaced intervals. Remember to use it at the same time(s) each day. Do not skip any doses.
Do not take more or less of this drug than prescribed, or stop taking it (or other HIV medicines) even for a short time, unless directed to do so by your doctor. Skipping or changing your dose without approval from your doctor may cause the amount of virus to increase.
Kaletra Cautions
Before taking this product, tell your doctor or pharmacist if you are allergic to either lopinavir or ritonavir; or to other HIV protease inhibitors such as amprenavir, indinavir or saquinavir; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
Before using this medication, tell your doctor or pharmacist your medical history, especially of: liver disease, diabetes, pancreatitis, high blood fat levels (cholesterol/triglycerides), heart problems (coronary artery disease, heart attack), bleeding problems (e.g., hemophilia), previous infection with certain diseases (e.g., hepatitis B infection, hepatitis C infection, tuberculosis).
Lopinavir/ritonavir may cause a condition that affects the heart rhythm (QT prolongation). QT prolongation can infrequently result in serious (rarely fatal) fast/irregular heartbeat and other symptoms (such as severe dizziness, fainting) that require immediate medical attention. The risk of QT prolongation may be increased if you have certain medical conditions or are taking other drugs that may affect the heart rhythm (see also Drug Interactions section). Before using lopinavir/ritonavir, tell your doctor or pharmacist if you have any of the following conditions: certain other heart problems (heart failure, slow heartbeat, QT prolongation in the EKG), family history of certain heart problems (QT prolongation in the EKG, sudden cardiac death).
Low levels of potassium or magnesium in the blood may also increase your risk of QT prolongation. This risk may increase if you use certain drugs (such as diuretics/"water pills") or if you have conditions such as severe sweating, diarrhea, or vomiting. Talk to your doctor about using lopinavir/ritonavir safely.
This medication should be used only when clearly needed during pregnancy. Discuss the risks and benefits with your doctor.
It is not known if this medication passes into breast milk. Because breast milk can transmit HIV, do not breast-feed.
Kaletra Side Effects
Diarrhea, nausea, vomiting, stomach upset, gas, headache, and trouble sleeping may occur. If any of these effects persist or worsen, notify your doctor or pharmacist promptly.
Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.
Tell your doctor immediately if any of these unlikely but serious side effects occur: joint/muscle pain, increased thirst, increased urination, blurred vision, confusion, persistent nausea/vomiting, severe stomach pain, yellowing of skin/eyes, dark urine, persistent fever, unusual tiredness.
Seek immediate medical attention if any of these rare but very serious side effects occur: symptoms of a heart attack (such as chest/jaw/left arm pain, shortness of breath, unusual sweating), severe dizziness, fainting, slow/fast/irregular heartbeat.
Changes in body fat may occur while you are taking this medication (e.g., increased fat in the upper back and stomach areas, decreased fat in the arms and legs). The cause and long-term effects of these changes are unknown. Discuss the risks and benefits of therapy with your doctor, as well as the possible role of exercise to reduce this side effect.
This medication may cause an increase in blood fat levels (cholesterol and triglycerides). Cholesterol and triglyceride testing should be done before and occasionally during treatment with this medication. Consult your doctor or pharmacist for more information.
A very serious allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of a serious allergic reaction may include: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.
This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.
Kaletra Active Ingredients
Lopinavir/Ritonavir