Product Details: Vytorin (ezetimibe/simvastatin)

PLEASE NOTE BRAND VYTORIN IS ALSO MARKETED INTERNATIONALLY UNDER THE NAME INEGY

Brand Name Options - Manufacturer: MSD-SP Ltd

Generic Options

What are Generics? A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, how it is taken, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name and works the same way in the body in the same amount of time.

The only differences between generics and their brand-name counterparts is the generics are less expensive and may look slightly different (e.g. different shape or color), as trademark laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to invent a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name drug and sell it at substantial discounts.

Description

This is a combination of two medicines used to treat high cholesterol. Ezetimibe works by reducing the amount of cholesterol that your body absorbs from your diet. Simvastatin is an HMG-CoA reductase inhibitor or "statin". It works by blocking an enzyme that is necessary for your body to make cholesterol. This medicine is used in combination with a low-cholesterol and low-fat diet. Keeping your cholesterol level under control may reduce your risk of heart problems and stroke. This medicine is not a cure for high cholesterol, but may help to control it. This medicine may also be used to treat other conditions as determined by your doctor.

Directions

Follow the directions for using this medicine provided by your doctor. An additional patient information leaflet is available with this medicine. Read it carefully. Ask your doctor, nurse, or pharmacist any questions that you may have about this medicine. This medicine may be taken on an empty stomach or with food. Take this medicine in the evening unless otherwise directed by your doctor. IF YOU ARE ALSO TAKING A BILE ACID SEQUESTRANT (such as cholestyramine, colestipol, or colesevelam), take this medicine at least 2 hours before or at least 4 hours after the bile acid sequestrant. DO NOT DRINK LARGE AMOUNTS OF GRAPEFRUIT JUICE (greater than 1 quart daily) or eat large amounts of grapefruit while taking this medicine. STORE THIS MEDICINE at room temperature between 68 and 77 degrees F (20 and 25 degrees C) in a tightly-closed container, away from heat and light. CONTINUE TAKING THIS MEDICINE even if you feel well. Most people with high cholesterol do not feel sick. Do not miss any doses. Taking this medicine at the same time each day will help you to remember. IF YOU MISS A DOSE OF THIS MEDICINE, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Cautions

DO NOT TAKE THIS MEDICINE if you have had an allergic reaction to it or are allergic to any ingredient in this product. IT MAY TAKE SEVERAL WEEKS for this medicine to work. DO NOT STOP USING THIS MEDICINE without first checking with your doctor. Your dosage is based on your medical condition, response to therapy, and the other medicines that you are taking. DO NOT EXCEED the recommended dose of this medicine. Laboratory and/or medical tests such as blood cholesterol levels, liver function tests, or muscle tests may be done at the start of therapy and while you are taking this medicine to monitor your progress or to check for side effects. KEEP ALL DOCTOR AND LABORATORY APPOINTMENTS while you are using this medicine. BEFORE YOU HAVE ANY MEDICAL OR DENTAL TREATMENTS, EMERGENCY CARE, OR SURGERY, tell the doctor or dentist that you are using this medicine. THIS MEDICINE MAY INCREASE YOUR RISK FOR LIVER PROBLEMS. Alcohol can also increase this risk. Before drinking alcohol, talk with your doctor about the safe use of this medicine and alcohol. THIS MEDICINE MAY CAUSE INJURY TO YOUR MUSCLES especially when taken at higher doses or when taken with certain other medicines. Contact your doctor immediately if you experience muscle pain or weakness, especially with a fever. Eating grapefruit or drinking grapefruit juice while you are taking this medicine may increase the amount of this medicine in your blood, which may increase your risk for serious side effects. Talk with your doctor before including grapefruit or grapefruit juice in your diet while you are taking this medicine. BEFORE YOU BEGIN TAKING ANY NEW MEDICINE, either prescription or over-the-counter, check with your doctor or pharmacist. FOR WOMEN: If you are able to become pregnant, talk with your doctor or pharmacist about the use of effective birth control while taking this medicine. DO NOT USE THIS MEDICINE if you are pregnant. IF YOU SUSPECT THAT YOU COULD BE PREGNANT, contact your doctor immediately. IT IS UNKNOWN IF THIS MEDICINE IS EXCRETED in breast milk. DO NOT BREAST-FEED while taking this medicine.

Side Effects

SIDE EFFECTS that may occur while taking this medicine include headache or tiredness. If they continue or are bothersome, check with your doctor. CONTACT YOUR DOCTOR IMMEDIATELY if you experience muscle aches, pain, tenderness, or weakness, especially if associated with unusual tiredness and a fever; yellowing of skin or eyes; dark urine; change in the amount of urine; stomach pain; ongoing nausea or vomiting; or blurred vision or vision changes. AN ALLERGIC REACTION to this medicine is unlikely, but seek immediate medical attention if it occurs. Symptoms of an allergic reaction include rash, itching, swelling, dizziness, or trouble breathing. If you notice other effects not listed above, contact your doctor, nurse, or pharmacist.

Active Ingredients

ezetimibe/simvastatin