Aranelle (Norethindrone Acetate / Ethinyl Estradiol)
(℞) Prescription required. Can not be split. Product of UK/EU. Shipped from United Kingdom. Aranelle is also marketed internationally under the name Synphase.
To comply with Canadian International Pharmacy Association regulations you are permitted to order a 3-month supply or the closest package size available based on your personal prescription. read more
Norethindrone Acetate / Ethinyl Estradiol Information
(ess' troe jen) (proe jes tin)Cigarette smoking increases the risk of serious side effects from oral contraceptives, including heart attacks, blood clots, and strokes. This risk is higher for women over 35 years of age and heavy smokers (15 or more cigarettes per day). If you take oral contraceptives, you should not smoke.
Before taking oral contraceptives,
- tell your doctor and pharmacist if you are allergic to estrogen, progestin, or any other medications.
- tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, and nutritional supplements you are taking. Be sure to mention any of the following: acetaminophen (APAP, Tylenol); antibiotics such as ampicillin (Principen), clarithromycin (Biaxin),erythromycin (E.E.S., E-Mycin, Erythrocin), isoniazid (INH, Nydrazid), metronidazole (Flagyl),minocycline (Dynacin, Minocin), rifabutin (Mycobutin), rifampin (Rifadin, Rimactane), tetracycline (Sumycin), and troleandomycin (TAO) (not available in the U.S.); anticoagulants ('blood thinners') such as warfarin (Coumadin); antifungals such as griseofulvin (Fulvicin, Grifulvin, Grisactin), fluconazole (Diflucan), itraconazole (Sporanox), and ketoconazole (Nizoral); atorvastatin (Lipitor); clofibrate (Atromid-S); cyclosporine (Neoral, Sandimmune); bosentan (Tracleer); cimetidine (Tagamet); danazol (Danocrine); delavirdine (Rescriptor); diltiazem (Cardizem, Dilacor, Tiazac); fluoxetine (Prozac, Sarafem, in Symbyax); HIV protease inhibitors such as indinavir (Crixivan) and ritonavir (Norvir); medications for seizures such as carbamazepine (Tegretol), felbamate (Felbatol), lamotrigine (Lamictal), oxcarbazepine (Trileptal), phenobarbital (Luminal, Solfoton), phenytoin (Dilantin), primidone (Mysoline), and topiramate (Topamax); modafinil (Provigil); morphine (Kadian, MS Contin, MSIR, others); nefazodone; rifampin (Rimactane, in Rifadin, in Rifater); oral steroids such as dexamethasone (Decadron, Dexone), methylprednisolone (Medrol), prednisone (Deltasone), and prednisolone (Prelone); temazepam (Restoril); theophylline (Theobid, Theo-Dur); thyroid medication such as levothyroxine (Levothroid, Levoxyl, Synthroid); verapamil (Calan, Covera, Isoptin, Verelan); vitamin C; and zafirlukast (Accolate). Your doctor may need to change the doses of your medications or monitor you carefully for side effects.
- if you are taking oral contraceptives that contain drosperinone (Beyaz, Gianvi, Loryna, Ocella, Safyral, Syeda, Yasmin, Yaz, and Zarah) tell your doctor and pharmacist if you are taking any of the medications listed above or any of the following: angiotensin-converting enzyme (ACE) inhibitors such as benazepril (Lotensin), enalapril (Vasotec), and lisinopril (Prinivil, Zestril); angiotensin II antagonists such as irbesartan (Avapro), losartan (Cozaar), and valsartan (Diovan); aspirin and other nonsteroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen (Advil, Motrin) and naproxen (Aleve, Naprosyn); diuretics ('water pills') such as amiloride (Midamor), spironolactone (Aldactone), and triamterene (Dyrenium); eplerenone (Inspra); heparin; or potassium supplements. Before taking Beyaz or Safyral, also tell your doctor or pharmacist if you are taking cholestyramine (Locholest, Prevalite, Questran), a folate supplement, methotrexate (Trexall), pyrimethamine (Daraprim), sulfasalazine (Azulfidine), or valproic acid (Depakene, Stavzor).
- tell your doctor what herbal products you are taking, especially St. John's wort.
- tell your doctor if you have or have ever had blood clots in your legs, lungs, or eyes; thrombophilia (condition in which the blood clots easily); coronary artery disease (clogged blood vessels leading to the heart); cerebrovascular disease (clogging or weakening of the blood vessels within the brain or leading to the brain); stroke or mini-stroke; an irregular heartbeat; heart disease; a heart attack; chest pain; diabetes that has affected your circulation; headaches that come along with other symptoms such as vision changes, weakness, and dizziness; high blood pressure; breast cancer; cancer of the lining of the uterus, cervix, or vagina; liver cancer, liver tumors, or other types of liver disease; yellowing of the skin or eyes during pregnancy or while you were using hormonal contraceptives (birth control pills, patches, rings, implants, or injections); unexplained abnormal vaginal bleeding; adrenal insufficiency (condition in which the body does not produce enough of certain natural substances needed for important functions such as blood pressure); or kidney disease. Also tell your doctor if you have recently had surgery or have been unable to move around for any reason. Your doctor may tell you that you should not take certain types of oral contraceptives or that you should not take any type of oral contraceptive if you have or have had any of these conditions.
- Also tell your doctor if anyone in your family has had breast cancer, if you are overweight, and if you have or have ever had problems with your breasts such as lumps, an abnormal mammogram (breast x-ray), or fibrocystic breast disease (swollen, tender breasts and/or breast lumps that are not cancer); high blood cholesterol or fats; diabetes; asthma; toxemia (high blood pressure during pregnancy); heart attack; chest pain; seizures; migraine headaches; depression; gallbladder disease; jaundice (yellowing of the skin or eyes); and excessive weight gain and fluid retention (bloating) during the menstrual cycle.
- do not take oral contraceptives if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking oral contraceptives, call your doctor immediately.
- if you miss periods while you are taking oral contraceptives, you may be pregnant. If you are using a 91-tablet packet and you miss one period, call your doctor. If you are using another type of packet according to the directions and you miss one period, you may continue to take your tablets. However, if you have not taken your tablets as directed and you miss one period or if you have taken your tablets as directed and you miss two periods, call your doctor and use another method of birth control until you have a pregnancy test. If you are using a 28-tablet packet that contains only active tablets, you will not expect to have periods on a regular basis, so it may be hard to tell if you are pregnant. If you are using this type of oral contraceptive, call your doctor and have a pregnancy test if you experience symptoms of pregnancy such as nausea, vomiting, and breast tenderness, or if you suspect you may be pregnant.
- if you are having surgery, including dental surgery, tell the doctor or dentist that you are taking oral contraceptives.
- you should know that oral contraceptives may cause a spotty darkening of the skin, especially on the face. If you have experienced changes in your skin color during pregnancy or while you were taking oral contraceptives in the past, you should avoid exposure to real or artificial sunlight while you are taking oral contraceptives. Wear protective clothing, sunglasses, and sunscreen.
- tell your doctor and pharmacist if you wear contact lenses. If you notice changes in vision or ability to wear your lenses while taking oral contraceptives, see an eye doctor.
- stomach cramps or bloating
- gingivitis (swelling of the gum tissue)
- increased or decreased appetite
- weight gain or weight loss
- brown or black skin patches
- hair growth in unusual places
- bleeding or spotting between menstrual periods
- changes in menstrual flow
- painful or missed periods
- breast tenderness, enlargement, or discharge
- swelling, redness, irritation, burning, or itching of the vagina
- white vaginal discharge
- severe headache
- severe vomiting
- speech problems
- dizziness or faintness
- weakness or numbness of an arm or leg
- crushing chest pain or chest heaviness
- coughing up blood
- shortness of breath
- leg pain
- partial or complete loss of vision
- double vision
- bulging eyes
- severe stomach pain
- yellowing of the skin or eyes
- loss of appetite
- extreme tiredness, weakness, or lack of energy
- dark-colored urine
- light-colored stool
- swelling of the hands, feet, ankles, or lower legs
- depression, especially if you also have trouble sleeping, tiredness, loss of energy, or other mood changes
- unusual bleeding
- menstrual bleeding that is unusually heavy or that lasts for longer than 7 days in a row