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(ep'' i nef' rin)
Before using epinephrine injection,
- tell your doctor and pharmacist if you are allergic to epinephrine, any other medications, sulfites, or any of the other ingredients in epinephrine injection. Your doctor may tell you to use epinephrine injection even if you are allergic to one of the ingredients because it is a life-saving medication. The epinephrine automatic injection device does not contain latex and is safe to use if you have a latex allergy.
- tell your doctor and pharmacist what other prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention any of the following: certain antidepressants such as amitriptyline, amoxapine, clomipramine (Anafranil), desipramine (Norpramin), doxepin (Silenor), imipramine (Tofranil), maprotiline, mirtazapine (Remeron), nortriptyline (Pamelor), protriptyline (Vivactil), and trimipramine (Surmontil); antihistamines such as chlorpheniramine (Chlor-Trimeton) and diphenhydramine (Benadryl); beta blockers such as propranolol (Hemangeol, Inderal LA, Innopran XL); digoxin (Lanoxicaps, Lanoxin); diuretics ('water pills'); ergot medications such as dihydroergotamine (D.H.E. 45, Migranal), ergoloid mesylates (Hydergine), ergotamine (Ergomar, in Cafergot, in Migergot), and methylergonovine (Methergine); levothyroxine (Levo-T, Levoxyl, Tironsint, others); medications for irregular heartbeat such as quinidine (in Nuedexta); and phentolamine (Oraverse, Regitine). Also tell your doctor if you are taking a monoamine oxidase inhibitor such as isocarboxazid (Marplan), phenelzine (Nardil), selegiline (Eldepryl, Emsam, Zelapar), and tranylcypromine (Parnate) or have stopped taking it within the past two weeks. Your doctor may need to monitor you carefully for side effects.
- tell your doctor if you have or have ever had chest pain, irregular heartbeat, high blood pressure, or heart disease; asthma; diabetes; hyperthyroidism (an overactive thyroid); pheochromocytoma (adrenal gland tumor); depression or other mental illness; or Parkinson's disease.
- tell your doctor if you are pregnant, plan to become pregnant, or are breastfeeding. Talk to your doctor about whether and when you should use epinephrine injection if you are pregnant.
- skin redness, swelling, warmth, or tenderness at the site of injection
- difficulty breathing
- pounding, fast, or irregular heartbeat
- nervousness, anxiety, or restlessness
- pale skin
- uncontrollable shaking of a part of your body