Cresemba (Isavuconazonium Sulfate )

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Isavuconazonium Sulfate Information

ISAVUCONAZONIUM (I sa vue KON a ZOE NE um) is an antifungal medicine. It is used to treat certain kinds of fungal infections.

This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.

They need to know if you have any of these conditions: -heart disease -history of irregular heartbeat -liver disease -an unusual or allergic reaction to isavuconazonium, isavuconazole, antifungals, other medicines, foods, dyes, or preservatives -pregnant or trying to get pregnant -breast-feeding

Take this medicine by mouth with a glass of water. Follow the directions on the prescription label. Do not cut, crush, or chew this medicine. You can take it with or without food. If it upsets your stomach, take it with food. Do not take with grapefruit juice. Take your medicine at regular intervals. Do not take your medicine more often than directed. Take all of your medicine as directed even if you think you are better. Do not skip doses or stop your medicine early. Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once. NOTE: This medicine is only for you. Do not share this medicine with others.

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

Do not take this medicine with any of the following medicines: -carbamazepine -grapefruit juice -ketoconazole -long acting barbiturates like phenobarbital, amobarbital -rifampin -ritonavir (high dose) -St. John's Wort This medicine may also interact with the following medications: -atorvastatin -bupropion -cyclosporine -digoxin -female hormones, like estrogens or progestins and birth control pills -lopinavir; ritonavir -midazolam -mycophenolate mofetil -sirolimus -tacrolimus

This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

Visit your doctor for regular check ups. Tell your doctor or healthcare professional if your symptoms do not start to get better or if they get worse. Some fungal infections can take many weeks or months of treatment to cure.

Side effects that you should report to your doctor or health care professional as soon as possible: -allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue -breathing problems -dark yellow or brown urine -irregular heartbeat -muscle cramps or pain -trouble passing urine or change in the amount of urine -yellowing of the eyes or skin Side effects that usually do not require medical attention (Report these to your doctor or health care professional if they continue or are bothersome.): -constipation -diarrhea -headache -nausea, vomiting -stomach pain -tiredness -trouble sleeping

This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Keep out of the reach of children. Store between 20 and 25 degree C (68 and 77 degrees F). Keep this medicine in the original container. Throw away any unused medicine after the expiration date.

NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.

Isavuconazonium sulfate Oral capsule