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(floo' ta mide)Flutamide may cause liver damage that can be serious or life-threatening. Tell your doctor if you have or have ever had liver disease. If you experience any of the following symptoms, call your doctor immediately: nausea, vomiting, loss of appetite, extreme tiredness, flu-like symptoms, muscle aches, soreness, pain in the upper right part of the stomach, yellowing of the skin or eyes, or dark urine. Keep all appointments with your doctor and the laboratory. Your doctor will order certain blood tests to check how well your liver is working before you begin taking flutamide, every month for the first 4 months of your treatment, and periodically for as long as your treatment continues. Talk to your doctor about the risks of taking flutamide.
Before taking flutamide,
- tell your doctor and pharmacist if you are allergic to flutamide or any other medications.
- tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention anticoagulants (''blood thinners'') such as warfarin (Coumadin).
- tell your doctor if you smoke and if you have or have ever had any inherited blood diseases such as glucose-6-phosphate dehydrogenase (G-6-PD) deficiency or hemoglobin M disease.
- you should know that flutamide is only for use in men. If taken by pregnant women, flutamide can harm the fetus. Women who are or may become pregnant should not take flutamide. If you take flutamide while you are pregnant, call your doctor.
- ask your doctor about the safe use of alcoholic beverages while you are taking flutamide. Flutamide may cause facial flushing, and drinking alcohol can make it worse.
- loss of appetite
- hot flashes
- decrease in sexual ability or desire
- breast enlargement in men
- swelling of the hands, feet, ankles, or lower legs
- blue-green or orange-colored urine