Humulin 30/70 (Insulin Recombinant Human / Insulin Isophane Human Biosynthetic)
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Insulin Recombinant Human / Insulin Isophane Human Biosynthetic Information
(in' su lin) (glar' geen)
Before using insulin glargine,
- tell your doctor and pharmacist if you are allergic to insulin (Humulin, Novolin, others), any of the ingredients of insulin glargine, or any other medications. Ask your pharmacist or check the manufacturer's patient information for a list of the ingredients.
- tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking. Be sure to mention any of the following: albuterol (Accuneb, Proair, Proventil, others); prescription and nonprescription medications that contain alcohol; angiotensin-converting enzyme inhibitors (ACE inhibitors) such as benazepril (Lotensin, in Lotrel), captopril, enalapril (Epaned, Vasotec, in Vaseretic), fosinopril, lisinopril (in Prinzide, in Zestoretic), moexipril, perindopril (in Prestalia), quinapril (Accupril, in Accuretic, in Quinaretic), ramipril (Altace), and trandolapril (Mavik, in Tarka); angiotensin receptor blockers (ARBs) such as azilsartan (Edarbi, in Edarbyclor), candesartan (Atacand, in Atacand HCT), eprosartan (Teveten), irbesartan (Avapro, in Avalide), losartan (Cozaar, in Hyzaar), telmisartan (Micardis, in Micardis HCT, in Twynsta), valsartan (Diovan, in Diovan HCT, in Exforge); atypical antipsychotics such as clozapine (Clozaril, Fazaclo, Versacloz) and olanzapine (Zyprexa, in Symbyax); beta-blockers such as atenolol (Tenormin, in Tenoretic), labetalol (Trandate), metoprolol (Lopressor, Toprol XL, in Dutoprol), nadolol (Corgard, in Corzide), and propranolol (Hemangeol, Inderal LA, Innopran XL); certain cholesterol-lowering medications such as fenofibrate (Antara, Lipofen, Triglide), gemfibrozil (Lopid), and niacin (Niacor, Niaspan); clonidine (Catapres, Catapres-TTS, Kapvay, in Clorpres, others); danazol; disopyramide (Norpace); diuretics ('water pills'); estrogens; fluoxetine (Prozac, Sarafem, Selfemra, in Symbyax); glucagon; guanethidine (not available in the U.S.); HIV protease inhibitors including atazanavir (Reyataz), indinavir (Crixivan), lopinavir (in Kaletra), nelfinavir (Viracept), ritonavir (Norvir, in Kaletra, in Viekira Pak), and saquinavir (Invirase); hormone replacement therapy (birth control pills, patches, rings, injections, or implants); isoniazid (Laniazid, in Rifamate, in Rifater); lithium (Lithobid); medications for asthma and colds; medications for mental illness and nausea; monoamine oxidase (MAO) inhibitors including isocarboxazid (Marplan), linezolid (Zyvox), phenelzine (Nardil), selegiline (Eldepryl, Emsam, Zelapar), and tranylcypromine (Parnate); octreotide (Sandostatin); oral contraceptives (birth control pills); oral medications for diabetes such as pioglitazone (Actos, in Actoplus Met, in Oseni, others) and rosiglitazone (Avandia); oral steroids such as dexamethasone, methylprednisolone (Medrol), and prednisone (Rayos); pentamidine (NebuPent, Pentam); pentoxifylline (Pentoxil); pramlintide (Symlin); propoxyphene (not available in the U.S.); reserpine; salicylate pain relievers such as aspirin, choline magnesium trisalicylate, choline salicylate, diflunisal, magnesium salicylate (Doan's, others), and salsalate; somatropin (Genotropin, Humatrope, Nutropin, Serostim, others); sulfa antibiotics; terbutaline; and thyroid medications. Your doctor may need to change the doses of your medications or monitor you carefully for side effects.
- tell your doctor if you have or have ever had nerve damage caused by your diabetes, heart failure, low blood levels of potassium; or any other medical conditions, including heart, liver or kidney disease.
- tell your doctor if you are pregnant, plan to become pregnant, or are breastfeeding. If you become pregnant while using insulin glargine, call your doctor.
- if you are having surgery, including dental surgery, tell the doctor or dentist that you are using insulin glargine.
- alcohol may cause a change in blood sugar. Ask your doctor about the safe use of alcoholic beverages while you are using insulin glargine.
- ask your doctor what to do if you get sick, experience unusual stress, or change your diet, exercise, or activity schedule. These changes can affect your blood sugar and the amount of insulin you will need.
- ask your doctor how often you should check your blood sugar. Be aware that hypoglycemia may affect your ability to perform tasks such as driving and ask your doctor if you need to check your blood sugar before driving or operating machinery.
- redness, swelling, pain, or itching at the injection site
- changes in the feel of your skin, skin thickening (fat build-up), or a little depression in the skin (fat breakdown)
- fever, cough, sore throat, or other signs of infection
- rash, hives, or itching all over the body
- difficulty breathing or swallowing
- fast pulse
- swelling of the eyes, face, lips, tongue, or throat
- muscle cramps
- abnormal heartbeat
- sudden weight gain
- swelling of ankles or feet
- shortness of breath
- vision changes