Jadenu (Deferasirox)

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Deferasirox Information

DEFERASIROX (de FER a sir ox) binds to iron in the blood. It helps to treat too much iron in the blood.

This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.

They need to know if you have any of these conditions: -a blood disorder -cancer -hearing problems -kidney disease -liver disease -low blood counts, like low white cell, platelet, or red cell counts -vision problems -an unusual or allergic reaction to deferasirox, other medicines, foods, dyes, or preservatives -pregnant or trying to get pregnant -breast-feeding

Take this medicine by mouth with a glass of water. Follow the directions on the prescription label. Take this medicine on an empty stomach. Take this medicine at regular intervals. Do not take it more often than directed. Do not stop taking except on your doctor's advice. Talk to your pediatrician regarding the use of this medicine in children. While this medicine may be prescribed for children as young as 2 years of age for selected conditions, precautions do apply.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once. NOTE: This medicine is only for you. Do not share this medicine with others.

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

-alosetron -antacids that have aluminum -aprepitant; fosaprepitant -birth control pills -certain medicines for blood pressure, heart disease, irregular heart beat like conivaptan, dronedarone, eplerenone, felodipine, nisoldipine, quinidine, tolvaptan -certain medicines for cholesterol like cholestyramine, colesevelam, colestipol, lovastatin, simvastatin -certain medicines for depression, anxiety, or psychotic disturbances like buspirone, duloxetine, lurasidone, melatonin, midazolam, pimozide, quetiapine, ramelteon, tacrine, triazolam -certain medicines for erectile dysfunction like sildenafil, vardenafil -certain medicines for HIV like darunavir, indinavir, lopinavir; ritonavir, maraviroc, saquinavir, ritonavir, tipranavir -certain medicines for migraine headaches like dihydroergotamine, eletriptan, ergotamine -certain medicines for pain like alfentanil, fentanyl -certain medicines for seizures like phenobarbital, phenytoin -certain medicines that lower your chance of fighting infection like budesonide, cyclosporine, dasatinib, everolimus, fluticasone, paclitaxel, sirolimus, tacrolimus -darifenacin -iron supplements or vitamins that have iron -other iron binders like deferoxamine -repaglinide -rifampin -theophylline and caffeine -ticagrelor -tizanidine

This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

Visit your doctor for regular check ups. You will need important blood work, vision tests, and hearing tests done while you are taking this medicine. You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medicine affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells. Avoid taking antacids containing aluminum at the same time as this medicine.

Side effects that you should report to your doctor or health care professional as soon as possible: -allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue -black or bloody stools or blood in vomit -changes in hearing -changes in vision -dark urine -fever or chills, sore throat -general ill feeling or flu-like symptoms -loss of appetite, nausea -right upper belly pain -trouble passing urine or change in the amount of urine -unusual bleeding or bruising -unusually weak or tired -yellowing of the eyes or skin Side effects that usually do not require medical attention (Report these to your doctor or health care professional if they continue or are bothersome.): -cough -diarrhea -headache -nausea, vomiting -stomach pain -trouble sleeping

This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Keep out of the reach of children. Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Protect from moisture. Throw away any unused medicine after the expiration date.

NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.

Deferasirox Oral tablet