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(fil gra' stim)
Before using filgrastim, filgrastim-sndz, or tbo-filgrastim,
- tell your doctor and pharmacist if you are allergic to filgrastim, pegfilgrastim (Neulasta), medications made from E. coli bacteria, or any other medications. Ask your pharmacist if you do not know if a medication you are allergic to is made from E. coli bacteria. Also tell your doctor if you or the person who will be injecting filgrastim or filgrastim-sndz for you is allergic to latex.
- tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention lithium (Lithobid). Your doctor may need to change the doses of your medications or monitor you carefully for side effects.
- tell your doctor if you are being treated with radiation therapy and if you have or have ever had chronic myeloid leukemia (a slowly progressing disease in which too many white blood cells are made in the bone marrow), myelodysplasia (problems with bone marrow cells that may develop into leukemia), or an enlarged spleen (an organ located under the ribs that is needed to clean the blood and fight infection).
- tell your doctor if you have sickle cell disease (a blood disease that may cause painful crises, a low number of red blood cells, infection, and damage to the internal organs). If you have sickle cell disease, you may be more likely to have a crisis during your treatment with filgrastim, filgrastim-sndz, or tbo-filgrastim. Drink plenty of fluids during your treatment with filgrastim, filgrastim-sndz, or tbo-filgrastim and call your doctor right away if you have a sickle cell crisis during your treatment.
- tell your doctor if you are pregnant, plan to become pregnant, or are breastfeeding. If you become pregnant while using filgrastim, filgrastim-sndz, or tbo-filgrastim, call your doctor.
- if you are having surgery, including dental surgery, tell the doctor or dentist that you are using filgrastim, filgrastim-sndz, or tbo-filgrastim.
- you should know that filgrastim, filgrastim-sndz, and tbo-filgrastim decrease the risk of infection, but does not prevent all infections that may develop during or after chemotherapy. Call your doctor if you develop signs of infection such as fever; chills; rash; sore throat; diarrhea; or redness, swelling, or pain around a cut or sore.
- redness, swelling, bruising, itching or a lump in the place where the medication was injected
- bone, joint, or muscle pain
- pain in the left upper part of the stomach or the tip of the left shoulder
- shortness of breath
- trouble breathing
- fast breathing
- swelling around the mouth, face, eyes, stomach, feet, ankles, or lower legs
- unusual bruising or purple markings under the skin
- unusual bleeding or bruising
- decreased urination