Truvada (Emtricitabine / Tenofovir Disoproxil Succinate)
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Emtricitabine / Tenofovir Disoproxil Succinate Information
(em tri sit' uh bean) (te noe' fo veer)Emtricitabine and tenofovir should not be used to treat hepatitis B virus infection (HBV; an ongoing liver infection). Tell your doctor if you have or think you may have HBV. Your doctor may test you to see if you have HBV before you begin your treatment with emtricitabine and tenofovir. If you have HBV and you take emtricitabine and tenofovir, your condition may suddenly worsen when you stop taking emtricitabine and tenofovir. Your doctor will examine you and order lab tests regularly for several months after you stop taking emtricitabine and tenofovir to see if your HBV has worsened. If you are taking emtricitabine and tenofovir to help prevent you from getting HIV, your doctor will test you to see if you have HIV before you begin your treatment and at least every 3 months during your treatment. Tell your doctor if you have had any of the following symptoms in the last month or if you have any of the following symptoms while taking emtricitabine and tenofovir to help prevent you from getting HIV: fever, tiredness, joint or muscle pain, rash, night sweats, vomiting, diarrhea, headache, sore throat, swollen neck or groin area. Tell your doctor if you think you may have been exposed to HIV. Emtricitabine and tenofovir does not always prevent HIV. Your doctor will order HIV tests at least every 3 months while you are taking emtricitabine and tenofovir to see if you have become infected with HIV. Emtricitabine and tenofovir should only be used in combination with other medications to treat HIV. If emtricitabine and tenofovir are used alone to treat HIV, your condition may become more difficult to treat. Keep all appointments with your doctor and the laboratory. Your doctor will order certain tests before and during your treatment to check your body's response to emtricitabine and tenofovir. Talk to your doctor about the risks of taking emtricitabine and tenofovir.
Before taking emtricitabine and tenofovir,
- tell your doctor and pharmacist if you are allergic to emtricitabine and tenofovir, any other medications, or any of the ingredients in emtricitabine and tenofovir tablets. Ask your pharmacist or check the Medication Guide for a list of the ingredients.
- tell your doctor and pharmacist what other prescription and nonprescription medications, vitamins, and nutritional supplements you are taking or plan to take. Be sure to mention any of the following: antiviral medications such as acyclovir (Sitavig, Zovirax), adefovir (Hepsera), cidofovir, ganciclovir (Cytovene), valacyclovir (Valtrex), and valganciclovir (Valcyte); aspirin and other nonsteroidal anti-inflammatory medications (NSAIDs) such as ibuprofen (Advil, Motrin) and naproxen (Aleve, Naprosyn); gentamicin; other medications for HIV or AIDS including atazanavir (Reyataz, in Evotaz), darunavir (Prezista, in Prezcobix), didanosine (Videx), emtricitabine (Emtriva, in Atripla, in Complera, in Genvoya, in Odefsey, in Stribild, in Truvada, others), lamivudine (Epivir, in Combivir, in Epzicom, in Trizivir, others), lopinavir and ritonavir (Kaletra), tenofovir (Viread, in Atripla, in Stribild, in Truvada, others); and other HIV medications containing emtricitabine and tenofovir (Atripla, Complera, Emtriva, Genvoya, Odefsey, Stribild, Vemlidy, Viread). If you are taking emtricitabine and tenofovir (Descovy) also tell your doctor if you are taking carbamazepine (Carbatrol, Equetro, Tegretol, others), oxcarbazepine (Oxtellar XR, Trileptal), phenobarbital, phenytoin (Dilantin, Phenytek), rifabutin (Mycobutin), rifampin (Rifadin, Rimactane, in Rifamate, in Rifater), rifapentine (Priftin), ritonavir (Norvir), and tipranavir (Aptivus). Your doctor may need to change the doses of your medications or monitor you carefully for side effects.
- tell your doctor what herbal products you are taking, especially St. John's wort. You should not take St. John's wort while you are taking emtricitabine and tenofovir (Descovy).
- tell your doctor if you have or have ever had the conditions mentioned in the IMPORTANT WARNING section, bone problems including osteoporosis (a condition in which the bones become thin and weak and break easily) or bone fractures, any type of infection that does not go away or that comes and goes such as tuberculosis (TB; a type of lung infection) or cytomegalovirus (CMV; a viral infection that may cause symptoms in people with weak immune systems), or liver or kidney disease.
- tell your doctor if you are pregnant, plan to become pregnant, or are breastfeeding. If you become pregnant while taking emtricitabine and tenofovir, call your doctor. You should not breastfeed if you are infected with HIV or if you are taking emtricitabine and tenofovir.
- you should know that while you are taking medications to treat HIV infection, your immune system may get stronger and begin to fight other infections that were already in your body. This may cause you to develop symptoms of those infections. If you have new or worsening symptoms during your treatment with emtricitabine and tenofovir, be sure to tell your doctor.
- difficulty falling asleep or staying asleep
- unusual dreams
- pain, burning or tingling in the hands or feet
- weight loss
- swelling of the face, throat, tongue, lips, eyes, hands, feet, ankles, or lower legs
- difficulty swallowing or breathing
- decreased urination
- difficult, painful, or frequent urination
- bone pain
- pain in upper right part of stomach
- loss of appetite
- flu-like symptoms
- unusual bleeding or bruising
- dark yellow or brown urine
- light-colored bowel movements
- yellowing of the skin or eyes
- feeling cold, especially in the arms or legs
- muscle pain
- fast or irregular heartbeat
- stomach pain with nausea and vomiting