Cabometyx (Cabozantinib) is an oral prescription medication used to treat several forms of cancer, including advanced renal cell carcinoma (RCC), hepatocellular carcinoma (HCC), and medullary thyroid cancer (MTC). It works by inhibiting multiple tyrosine kinases involved in tumor growth, angiogenesis, and drug resistance. Cabometyx is typically taken once daily in tablet form and is part of long-term cancer therapy.
Without insurance, Cabometyx (Cabozantinib) can be extremely expensive, with U.S. retail pharmacy prices ranging from $26,682 to over $26,900 for a 30-day supply.
Key Takeaways
Online Pharmacies Offer Significant Savings: CIPA-certified international pharmacies such as DrugMart list Cabometyx (Cabozantinib) at $9,891.68 for a 30-tablet supply—saving more than 60% compared to U.S. retail pharmacies. Purchase from Planet Drugs Direct
U.S. Pharmacies Charge $26,682–$26,929 Monthly Without Insurance: Retailers such as CVS and Walgreens list Cabometyx (Cabozantinib) at approximately $26,700 or higher for a 30-day supply.
Cabometyx Is Covered by Medicare and Private Insurance: Coverage varies by plan. It is usually placed on Tier 5 (specialty tier) and often requires prior authorization. Out-of-pocket costs depend on formulary placement, deductible, and benefit phase.
Cheapest Online Pharmacies for Cabometyx (Cabozantinib)
Here’s the best online pharmacies to purchase Cabometyx (Cabozantinib) for cheap:
Pharmacy | Prescription Required | Price (30 Tablets) | Dosage | Website |
Planet Drugs Direct | Yes | $9,786.99 | 20mg | |
DrugMart | Yes | $9,891.68 | 20mg | |
Blink Health | Yes | $26,724.05 | 20mg |
Prices as of July 1, 2025. May vary by quantity, shipping origin, and dosage strength.
U.S. Retail Prices for Cabometyx (Cabozantinib)
U.S. retail prices for Cabometyx (Cabozantinib):
Pharmacy | Retail Price (30-Day Supply) |
CVS Pharmacy | $26,682.00 |
Walgreens | $26,929.40 |
Prices as of July 1, 2025. Actual costs may vary by location and insurance status.
How to Save on Cabometyx (Cabozantinib)
Here’s how to save on Cabometyx (Cabozantinib):
1. Use Medicare Part D or Commercial Insurance
Cabometyx is covered by most Medicare Part D and commercial insurance plans. However, it is generally placed on higher specialty tiers (such as Tier 5), resulting in high coinsurance or copays.
Tip: Use your plan’s drug formulary or the Medicare Plan Finder tool to verify coverage and estimate actual out-of-pocket costs.
2. Exelixis Access Services (EASE) Program
Co-pay assistance: Eligible commercially insured patients may pay as little as $0.
Free 30-day trial: Available for new patients who meet program criteria.
Support for prior authorization and appeals: EASE provides help navigating insurance barriers and paperwork.
Visit Exelixis Access Services or call 1-844-900-EASE (3273) for enrollment and eligibility details.
3. CIPA-Certified Online Pharmacies
Ordering from licensed international pharmacies like Planet Drugs Direct can reduce the cost of Cabometyx (Cabozantinib) by up to 65%. A valid prescription is required, and medications are shipped from regulated pharmacies from Canada.
Ready to order? Purchase from Planet Drugs Direct.
Common Questions About Cabometyx (Cabozantinib)
Common questions and answers about Cabometyx (Cabozantinib):
1. Is Cabometyx (Cabozantinib) covered by Medicare?
Yes. Most Medicare Part D plans include Cabometyx in their formularies. However, it is typically placed on a high-cost specialty tier (Tier 5) and may require prior authorization. Patients should contact their plan provider to confirm coverage, costs, and any documentation needed.
2. Are there savings programs for Cabometyx (Cabozantinib)?
Yes. The Exelixis Access Services (EASE) program offers:
Co-pay support for eligible commercially insured patients
A 30-day free trial program
Assistance with insurance approvals, prior authorizations, and appeals
Financial assistance referrals for uninsured or underinsured patients
3. How much will Cabometyx (Cabozantinib) cost per year?
Here’s how much Cabometyx (Cabozantinib) could cost per year for long-term treatment of advanced kidney cancer (renal cell carcinoma), liver cancer (hepatocellular carcinoma), and differentiated thyroid cancer:
Purchase Method | Monthly Estimate | Annual Estimate |
U.S. Retail Pharmacies | $26,682 – $26,929 | $320,184 – $323,148 |
CIPA Online Pharmacy (DrugMart) | ~$9,891.68 | ~$118,700 |
Medicare Part D (2025 cap) | Max $2,000/year | $2,000 |
EASE Copay Program | As low as $0 | Varies (max benefit applies) |
4. Why is Cabometyx (Cabozantinib) so expensive?
Several factors contribute to the high cost of Cabometyx (Cabozantinib):
Research and Development Costs: Developing oncology drugs like Cabometyx involves substantial investment in laboratory research, multiple phases of clinical trials, and FDA regulatory review. These costs—often in the hundreds of millions—are reflected in the drug’s price.
Complex Manufacturing: Cabometyx is a complex small-molecule therapy that requires advanced manufacturing techniques and strict quality controls. These processes add to the cost of production and distribution.
Limited Competition: Cabometyx is one of the few approved treatments for certain advanced cancers (e.g., RCC, HCC), giving the manufacturer pricing leverage in the absence of equally effective alternatives.
Insurance Coverage Variability: Out-of-pocket costs for patients are heavily influenced by their insurance plan’s tier placement, coinsurance, and deductible. Specialty-tier placement in Medicare Part D can lead to higher copays unless offset by manufacturer assistance or the 2025 out-of-pocket cap.
Dosage and Dispensing Pharmacy: The total cost of Cabometyx can also vary based on the prescribed dose (e.g., 20mg vs. 60mg) and which pharmacy fills the prescription. Some retail pharmacies charge significantly more than online or international options.
Overall Cost of Cancer Treatment: As part of a broader oncology regimen, Cabometyx contributes to the already high cost of cancer care. In some clinical settings, studies have raised concerns about its cost-effectiveness relative to other therapies.
While the list price is high, access programs, insurance coverage, and international pharmacy options may substantially lower costs for eligible patients.
Rely on PlanetDrugsDirect.com to Buy Online Prescription Cabometyx
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Sources
Bausch & Lomb Incorporated. Xiidra Cost & Savings Programs. Accessed July 2, 2025. https://www.xiidra.com/xiidra-cost/
Bausch & Lomb Incorporated. Xiidra (lifitegrast ophthalmic solution) Prescribing Information [PDF]. Accessed July 2, 2025. https://pi.bausch.com/globalassets/pdf/packageinserts/pharma/xiidra-prescribing-information.pdf
