IBRANCE® (palbociclib) is an oral prescription medication used to treat hormone receptor-positive (HR+), human epidermal growth factor receptor 2-negative (HER2–) advanced or metastatic breast cancer. It is commonly prescribed in combination with hormone therapy and taken once daily for 21 consecutive days followed by 7 days off, in a 28-day treatment cycle.
Without insurance, IBRANCE can be prohibitively expensive, with U.S. retail prices approaching $8,000 for a 21-day supply.
Key Takeaways
Online Pharmacies Offer Major Discounts: Licensed international pharmacies such as DrugMart and Planet Drugs Direct list IBRANCE® (palbociclib) 125 mg at nearly 50% off U.S. retail prices when purchased in 63-capsule (3-month) quantities. Purchase from Planet Drugs Direct.
U.S. Retail Pharmacy Prices Range from $7,974 to $8,031 for 21 Capsules: Prices vary slightly between Walgreens and CVS locations.
Medicare and Commercial Insurance May Cover IBRANCE: Most Medicare Part D plans include IBRANCE, but prior authorization and step therapy are commonly required.
Eligible Patients May Pay $0 with a Pfizer Savings Card: The Pfizer Oncology Together Co-Pay Assistance Program provides up to $10,000 annually for commercially insured patients.
Cheapest Online Pharmacies for IBRANCE® (Palbociclib)
Cheapest places to purchase IBRANCE® (palbociclib) online:
Pharmacy | Prescription Required | Price (21 Capsules) | Dosage | Website |
Blink Health | Yes | $16,696.39 | 125mg | |
Planet Drugs Direct | Yes | ~$9,096.00 (prorated) | 125mg | |
DrugMart | Yes | ~$9,209.79 (prorated) | 125mg |
Prices as of July 1, 2025. Note: Prices from DrugMart ($27,579.36) and Planet Drugs Direct ($27,207.99) reflect 63-capsule packages (3 full cycles). Prorated prices are based on 21-capsule equivalents.
U.S. Retail Pharmacy Prices for IBRANCE® (Palbociclib)
U.S. retail pharmacy prices for IBRANCE® (palbociclib):
Pharmacy | Retail Price (21 Capsules) | Price per Capsule |
CVS | $7,974.31 | $797.43 |
CVS inside Target | $7,974.31 | $797.43 |
Walgreens | $8,031.55 | $803.15 |
Prices current as of July 1, 2025. Actual prices may vary based on location and insurance status.
How to Save on IBRANCE® (Palbociclib)
Here’s how to save on IBRANCE® (palbociclib):
1. Use Commercial Insurance or Medicare
IBRANCE is typically covered under commercial and Medicare Part D plans, but it is usually classified as a specialty drug. Coverage often involves:
Prior Authorization: Your doctor may need to submit medical justification before your plan approves coverage.
Step Therapy Requirements: Some plans require trying alternative treatments first.
High Cost-Sharing: Copays and coinsurance can be significant depending on your coverage phase.
2. Pfizer Oncology Together Co-Pay Assistance
Commercially insured patients may qualify for:
$0 monthly copay
Up to $10,000 in annual savings
Support with insurance approvals and appeals
Not available to patients enrolled in government-funded programs such as Medicare, Medicaid, TRICARE, or Veterans Affairs coverage.
3. Medicare and Financial Aid Programs
For Medicare beneficiaries:
Part D Coverage: Most Medicare Part D plans cover IBRANCE, often requiring prior authorization.
Extra Help: The Medicare Low-Income Subsidy (LIS) or Extra Help program may reduce copayments significantly.
Future Savings: IBRANCE has been selected for Medicare price negotiation under the Inflation Reduction Act, which may reduce long-term costs.
Patients can also apply for manufacturer assistance through Pfizer or seek nonprofit foundation aid.
4. CIPA-certified Online Pharmacy
CIPA-certified online pharmacies can save you up to 50% off your typical prescription medication costs for IBRANCE® (palbociclib).
Ready to purchase? Purchase from Planet Drugs Direct.
Annual Cost Comparison for IBRANCE® (Palbociclib)
Here is what the annual cost for IBRANCE® (palbociclib) may be based on your choice of where to purchase:
Purchase Method | Monthly Estimate | Annual Estimate |
U.S. Retail Pharmacy | $7,974 – $8,031 | $95,688 – $96,378 |
CIPA-certified Online Pharmacy | ~$9,096 – $9,209 | ~$36,400 – $36,850 |
Medicare Part D (2025 cap) | Max $2,000/year | $2,000 |
Pfizer Co-Pay Program | As low as $0/month | Varies (max $10,000) |
Common Questions About IBRANCE® (Palbociclib)
Common questions and answers about IBRANCE® (palbociclib):
Is IBRANCE covered by Medicare?
Yes. Most Medicare Part D plans include IBRANCE, though prior authorization and step therapy may apply.
How much does IBRANCE cost per month without insurance?
Retail prices in the U.S. range from $7,974 to $8,031 for a 21-capsule supply. International pharmacies offer similar supplies for just over $9,000.
Who qualifies for Pfizer’s Co-Pay Program?
Only commercially insured patients qualify. Government-insured individuals (Medicare, Medicaid, TRICARE) are not eligible.
Can Medicare patients get help paying for IBRANCE?
Yes. Financial assistance may be available through Medicare’s Extra Help program, nonprofit foundations, or Pfizer’s patient assistance program for the uninsured or underinsured.
Rely on PlanetDrugsDirect.com to Buy Online Prescription Ibrance
As a trusted prescription referral service, we offer important benefits whenever you order online. Each of our partner pharmacies and/or government-approved dispensaries is committed to providing the best experience possible of any online prescription referral service on the internet. We offer:
Low prices
Quick turn-around times
Generic and brand-name medications
Unparalleled customer service
Sources
Pfizer Inc. IBRANCE Financial Support Resources. Accessed July 1, 2025. https://www.ibrance.com/financial-support-resources
U.S. Food & Drug Administration. IBRANCE Prescribing Information. Updated April 2019. https://www.accessdata.fda.gov/drugsatfda_docs/label/2019/207103s008lbl.pdf
