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(loe mus' teen)Lomustine can cause a severe decrease in the number of blood cells in your bone marrow. A decrease in the number of blood cells in your body may cause certain symptoms and may increase the risk that you will develop a serious infection or bleeding. If you experience any of the following symptoms, call your doctor immediately: fever, sore throat, ongoing cough and congestion, or other signs of infection; unusual bleeding or bruising, bloody or black, tarry stools; bloody vomit; or vomiting blood or brown material that resembles coffee grounds. Taking too much lomustine or taking it too often can cause serious, life-threatening problems. Take only one dose of lomustine every six weeks. Keep all appointments with your doctor and the laboratory. Your doctor will order laboratory tests before, during, and after your treatment to check your body's response to lomustine to see if your blood cells, liver, kidneys, and lungs are affected by this medication.
Before taking lomustine,
- tell your doctor and pharmacist if you are allergic to lomustine, any other medications, or any of the ingredients in lomustine capsules. Ask your pharmacist for a list of the ingredients.
- tell your doctor and pharmacist what other prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take.
- you should know that lomustine may decrease fertility in men and women. However, you should not assume that you or your partner cannot become pregnant. Tell your doctor if you are pregnant or plan to become pregnant. If you are female, you should use birth control to prevent pregnancy during your treatment with lomustine and for at least 2 weeks after your final dose. If you are male, you and your female partner should use birth control during your treatment with lomustine and continue for 4 months after your final dose. If you or your partner become pregnant while taking lomustine, call your doctor. Lomustine may harm the fetus.
- tell your doctor if you are breast-feeding or plan to breast-feed. You should not breast-feed while taking lomustine and for 2 weeks after your final dose.
- loss of appetite
- sores in the mouth and throat
- unusual tiredness or weakness
- pale skin
- hair loss
- unsteady walk
- slurred speech
- difficulty breathing
- shortness of breath
- dry cough
- chest pain
- decreased urination;
- swelling of the face, arms, hands, feet, ankles, or lower legs.
- yellowing or eyes and skin
- sudden change or loss of vision