Matulane (Procarbazine Hydrochloride)
Sorry, we currently do not carry this product.
Procarbazine Hydrochloride Information
(proe kar' ba zeen)Procarbazine should be taken only under the supervision of a doctor with experience in the use of chemotherapy medications. Keep all appointments with your doctor and the laboratory. Your doctor will order laboratory tests before, during and after your treatment to check your body's response to procarbazine.
Before taking procarbazine,
- tell your doctor and pharmacist if you are allergic to procarbazine, any other medications, or any of the ingredients in procarbazine capsules. Ask your pharmacist for a list of the ingredients.
- tell your doctor if you are taking or you plan to take any of the following prescription or non-prescription medications: certain antidepressants including amitriptyline (Elavil) and imipramine (Tofranil); medications for asthma; medications for allergies, hay fever; medications containing alcohol (cough and cold products, such as Nyquil, and other liquid products); and nasal decongestants, including nose drops and sprays. Your doctor may tell you not to take these medications with procarbazine and may suggest other treatment(s).
- tell your doctor and pharmacist what other prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention any of the following: barbiturate medications such as phenobarbital; medications for high blood pressure; medications for nausea or mental illness; opioid (narcotic) medications for pain; sedatives; sleeping pills; and tranquilizers. Your doctor may need to change the doses of your medications or monitor you carefully for side effects. Many other medications may also interact with procarbazine, so be sure to tell your doctor about all the medications you are taking, even those that do not appear on this list.
- tell your doctor if you have received radiation therapy or other chemotherapy within the last 4 weeks.
- tell your doctor if you have or have ever had kidney or liver disease.
- tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. You should not become pregnant or breast-feed while you are taking procarbazine. If you become pregnant while receiving procarbazine, call your doctor. Procarbazine may harm the fetus.
- know that you should not drink alcoholic beverages (including beer and wine) while taking this drug. Alcohol may cause an upset stomach, vomiting, stomach cramps, headaches, sweating, and flushing (redness of the face).
- tell your doctor if you use tobacco products. Smoking may increase the risk that you will develop other cancers. You should stop smoking.
- loss of appetite
- stomach pain
- dryness of mouth
- changes in skin color
- hair loss
- difficulty falling asleep or staying asleep
- bone, joint, or muscle pain
- increased urination
- sores in the mouth and throat
- severe or ongoing diarrhea
- pain, burning, numbness, pricking, or tingling in the hands or feet or on the skin
- uncontrollable shaking of a part of your body
- hallucinating (seeing things or hearing voices that do not exist)
- vision changes
- fast or irregular heartbeat
- fever, sore throat, chills, or other signs of infection
- unusual bruising or bleeding
- black, tarry stools
- red urine
- difficulty breathing or swallowing
- yellowing of the skin or eyes