Before using ciprofloxacin injection,
tell your doctor and pharmacist if you are allergic or have had a severe reaction to ciprofloxacin or any other quinolone or fluoroquinolone antibiotic such as gatifloxacin (Tequin) (not available in the U.S.), gemifloxacin (Factive), levofloxacin (Levaquin), lomefloxacin (Maxaquin) (not available in the U.S.), moxifloxacin (Avelox), nalidixic acid (NegGram) (not available in the U.S.), norfloxacin (Noroxin) (not available in the U.S.), ofloxacin (Floxin), and sparfloxacin (Zagam) (not available in the U.S.), or if you are allergic to any other medications.
tell your doctor if you are taking tizanidine (Zanaflex). Your doctor will probably tell you not to use ciprofloxacin injection while you are taking this medication.
tell your doctor and pharmacist what other prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention the medications listed in the IMPORTANT WARNING section and any of the following: anticoagulants ('blood thinners') such as warfarin (Coumadin, Jantoven); certain antidepressants; antipsychotics (medications to treat mental illness) such as clozapine (Clozaril, FazaClo, Versacloz) and olanzapine (Zyprexa, in Symbax); athizromycin (Zithromax, Zmax); caffeine or medications that contain caffeine (Excedrin, NoDoz, Vivarin, others); clarithromycin (Biaxin, in Prevpac); cyclosporine (Gengraf, Neoral, Sandimmune); diuretics ('water pills'); duloxetine (Cymbalta); erythromycin (E.E.S., Eryc, Eryped, others); lidocaine (Xylocaine); certain medications for irregular heartbeat such as amiodarone (Cordarone, Nexterone, Pacerone), disopyramide (Norpace), procainamide , quinidine, and sotalol (Betapace, Betapace AF, Sorine, Sotylize); medications for diabetes that are taken by mouth such as glimepiride (Amaryl, in Duetact), and glyburide (DiaBeta, Glynase, in Glucovance); methotrexate (Otrexup, Rasuvo, Trexall); nonsteroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen (Advil, Motrin, others) and naproxen (Aleve, Naprosyn, others); phenytoin (Dilantin, Phenytek); probenecid (Probalan, in Col-Probenecid); ropinirole (Requip); sildenafil (Revatio, Viagra);or theophylline (Elixophyllin, Theo-24, Uniphyl others). Your doctor may need to change the doses of your medications or monitor you carefully for side effects. Many other medications may also interact with ciprofloxacin, so be sure to tell your doctor about all the medications you are taking, even those that do not appear on this list.
tell your doctor if you or anyone in your family has or has ever had prolonged QT interval (a rare heart problem that may cause irregular heartbeat, fainting, or sudden death) or if you have or have ever had an irregular heartbeat, heart failure (condition in which the heart is unable to pump enough blood to the other parts of the body), a heart attack, or a slow heartbeat; or have a low level of potassium or magnesium in your blood. Also tell your doctor if you have or have ever had liver disease.
tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while using ciprofloxacin injection, call your doctor.
Do not drive a car, operate machinery, or participate in activities requiring alertness or coordination until you know how this medication affects you.
plan to avoid unnecessary or prolonged exposure to sunlight or ultraviolet light (tanning beds and sunlamps) and to wear protective clothing, sunglasses, and sunscreen. Ciprofloxacin injection may make your skin sensitive to sunlight or ultraviolet light. If your skin becomes reddened, swollen, or blistered, like a bad sunburn, call your doctor.