Before taking voriconazole,
tell your doctor and pharmacist if you are allergic to voriconazole; other antifungal medications such as fluconazole (Diflucan), itraconazole (Onmel, Sporanox), or ketoconazole (Nizoral);any other medications, or any of the ingredients in voriconazole tablets and suspension. Ask your pharmacist for a list of the ingredients in voriconazole tablets and suspension.
do not take voriconazole if you are taking any of the following medications: astemizole (Hismanal) (not available in the United States); carbamazepine (Carbatrol, Epitol, Equetro, Tegretol, Teril); cisapride (Propulsid); efavirenz (Sustiva, in Atripla); ergot-type medications such as dihydroergotamine (D.H.E. 45, Migranal), ergoloid mesylates (Hydergine), ergotamine (Ergomar, in Cafergot, in Migergot), and methylergonovine (Methergine); phenobarbital; pimozide (Orap); quinidine (Quinidex, in Nuedexta); rifabutin (Mycobutin); rifampin (Rifadin, Rimactane, in Rifamate, in Rifater); ritonavir (Norvir, in Kaletra); sirolimus (Rapamune); St. John's wort; and terfenadine (Seldane) (not available in the United States).
tell your doctor and pharmacist what other prescription and nonprescription medications, vitamins, and nutritional supplements you are taking. Be sure to mention any of the following: ; anticoagulants ('blood thinners') such as warfarin (Coumadin, Jantoven); benzodiazepines such as alprazolam (Niravam, Xanax), midazolam, and triazolam (Halcion); calcium channel blockers such as amlodipine (Norvasc, in Amturnide, in Tekamlo), felodipine (Plendil), isradipine, nicardipine (Cardene), nifedipine (Adalat, Afeditab, Procardia), nimodipine (Nymalize), and nisoldipine (Sular); cholesterol-lowering medications (statins) such as atorvastatin (Lipitor, in Caduet, in Liptruzet), fluvastatin (Lescol), lovastatin (Altoprev, in Advicor), pravastatin (Pravachol), and simvastatin (Zocor, in Simcor, in Vytorin); cyclosporine (Gengraf, Neoral, Sandimmune); everolimus (Afinitor, Zortress); fentanyl (Abstral, Actiq, Fentora, Lazanda, Subsys); medications for diabetes such as glipizide (Glucotrol), glyburide (Diabeta, Glynase, , in Glucovance), and tolbutamide; medications for HIV such as delavirdine (Rescriptor), nelfinavir (Viracept), nevirapine (Viramune), and saquinavir (Invirase); methadone (Dolophine, Methadose); nonsteroidal anti-inflammatory drugs (diclofenac, ibuprofen), oral contraceptives; oxycodone (Oxecta, Oxycontin, in Oxycet, in Percocet, in Percodan, in Roxicet, in Xartemis); phenytoin (Dilantin, Phenytek); proton-pump inhibitors such as esomeprazole (Nexium, in Vimovo), lansoprazole (Prevacid), omeprazole (Prilosec, in Prevpac), pantoprazole (Protonix), and rabeprazole (AcipHex); tacrolimus (Astagraf, Prograf); vinblastine; and vincristine. Many other medications may also interact with voriconazole, so be sure to tell your doctor about all the medications you are taking, even those that do not appear on this list. Your doctor may need to change the doses of your medications or monitor you carefully for side effects.
tell your doctor if you have ever been treated with chemotherapy medications for cancer, and if you have or have ever had a prolonged QT interval (a rare heart problem that may cause irregular heartbeat, fainting, or sudden death), or if you have or ever had a slow or irregular heartbeat, low blood levels of potassium, magnesium, or calcium, cardiomyopathy (enlarged or thickened heart muscle that stops the heart from pumping blood normally), cancer of the blood cells, any condition that makes it difficult for you to digest sucrose or lactose, or liver or kidney disease.
tell your doctor if you are pregnant, plan to become pregnant, or are breastfeeding. If you become pregnant while taking voriconazole, call your doctor immediately.
if you are having surgery, including dental surgery, tell the doctor or dentist that you are taking voriconazole.
you should know that voriconazole may cause blurred vision or other problems with your eyesight and may make your eyes sensitive to bright light. Do not drive a car at night while taking voriconazole. Do not drive a car during the day or operate machinery if you have any problems with your vision while you are taking this medication.
plan to avoid unnecessary or prolonged exposure to sunlight and to wear protective clothing, sunglasses, and sunscreen. Voriconazole may make your skin sensitive to sunlight.