Before taking demeclocycline,
tell your doctor and pharmacist if you are allergic to demeclocycline, tetracycline, minocycline, doxycycline, any other medications, or any of the ingredients in demeclocycline tablets. Ask your pharmacist for a list of the ingredients.
tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take, especially anticoagulants ('blood thinners') such as warfarin (Coumadin, Jantoven), and penicillin. Your doctor may need to change the doses of your medications or monitor you carefully for side effects.
be aware that antacids containing magnesium, aluminum, or calcium, calcium supplements, iron products, and laxatives containing magnesium interfere with demeclocycline, making it less effective. Take demeclocycline 2 hours before or6 hours after antacids, calcium supplements, and laxatives containing magnesium. Take demeclocycline 2 hours before or4 hours after iron preparations and vitamin products that contain iron.
tell your doctor if you have or have ever had lupus (condition in which the immune system attacks many tissues and organs including the skin, joints, blood, and kidneys), or kidney or liver disease.
you should know that demeclocycline may decrease the effectiveness of hormonal contraceptives (birth control pills, patches, rings, or injections). Talk to your doctor about using another form of birth control.
tell your doctor if you are pregnant, plan to become pregnant, or are breastfeeding. If you become pregnant while taking demeclocycline, call your doctor immediately. Demeclocycline can harm the fetus.
plan to avoid unnecessary or prolonged exposure to sunlight and to wear protective clothing, sunglasses, and sunscreen. Demeclocycline may make your skin sensitive to sunlight. Tell your doctor right away if you get a sunburn.
you should know that when demeclocycline is used during pregnancy or in babies or children up to age 8, it can cause the teeth to become permanently stained. Demeclocycline should not be used in children under age 8 unless your doctor decides it is needed.