Changes coming to U.S. import regulations, effective August 29th, 2025. All shipments may be affected. Read more for continued updates.
(Guanfacine Hydrochloride)
Prescription required. Can not be split. Product of Canada. Shipped from Canada. Intuniv is also marketed internationally under the name Intuniv XR.
Prescription required. Can not be split. Product of Canada. Shipped from Canada.
Prescription required. Can not be split. Product of Canada. Shipped from Canada. Intuniv is also marketed internationally under the name Intuniv XR.
Prescription required. Can not be split. Product of Canada. Shipped from Canada.
Prescription required. Can not be split. Product of UK/EU. Shipped from United Kingdom. Intuniv is also marketed internationally under the name Intuniv PR.
Prescription required. Can not be split. Product of Canada. Shipped from Canada.
Prescription required. Can not be split. Product of Canada. Shipped from Canada. Intuniv is also marketed internationally under the name Intuniv XR.
Prescription required. Can not be split. Product of Canada. Shipped from Canada.
Guanfacine, the active ingredient of Intuniv, is a prescription medication used to treat high blood pressure (hypertension) in some instances. However, under the brand name Intuniv (and its generic forms of guanfacine ER), the medication is used to manage attention deficit hyperactivity disorder (ADHD).
At the discretion of a healthcare provider, guanfacine may also be prescribed for other purposes not listed in this guide.
To comply with Canadian International Pharmacy Association regulations you are permitted to order a 3-month supply or the closest package size available based on your personal prescription. read more
Who Should Not Take Guanfacine
Do not use guanfacine if you are allergic to it.
Guanfacine Dosage and Age
Doses above 4 mg/day have not been evaluated in patients aged 6-12 years.
Doses above 7 mg/day have not been evaluated in patients aged 13-17 years.
Tell Your Doctor If You Have a History Of:
Heart problems, coronary artery disease, or heart rhythm disorders.
A heart attack or stroke.
High or low blood pressure.
Liver or kidney disease.
Guanfacine can cause blood pressure levels to drop, which can lead to symptoms like dizziness or fainting. When guanfacine is stopped suddenly, it can lead to a condition called rebound hypertension, where blood pressure levels rise. Heart rate can also increase. When discontinuing guanfacine, working with a healthcare provider to develop a plan to slowly decrease the dose is helpful. This can help prevent side effects.
Pregnancy and Breastfeeding
The effects of guanfacine on an unborn baby are largely unknown. Tell your doctor if you are pregnant or planning to become pregnant.
It is not known whether guanfacine passes into breast milk. Consult your doctor before breastfeeding.
Follow all prescription instructions and medication guides.
Avoid taking guanfacine with high-fat foods, as this may increase the absorption rate.
Swallow Intuniv tablets whole without crushing, chewing, or breaking them.
It may be recommended to take guanfacine at bedtime to reduce daytime drowsiness.
Missed Dose
Take the missed dose as soon as you remember unless it’s close to the next dose. Do not double doses.
Contact your doctor if you miss more than two consecutive doses.
Overdose
Overdose symptoms may include severe drowsiness, slow heart rate, or fainting. Seek emergency medical help or call the Poison Help line at 1-800-222-1222.
Serious Side Effects
Seek emergency medical attention if you experience:
Signs of an allergic reaction (hives, swelling, difficulty breathing).
Severe drowsiness, labored breathing, or other signs of overdose.
Slow heartbeats or a light-headed feeling as if you might pass out.
Common Side Effects
Drowsiness.
Dizziness.
Low blood pressure.
Fatigue.
Irritability.
Dry mouth.
Stomach pain.
Constipation.
Decreased appetite.
Inform your doctor of all medications you are taking, including over-the-counter drugs, vitamins, and herbal supplements.
Guanfacine may interact with:
Ketoconazole or barbiturates.
Sedatives like Valium or Xanax.
Blood pressure medications or mental health treatments.
Store guanfacine at room temperature, away from moisture, heat, and light.
Keep all medications out of reach of children and pets.
The content on this page is for informational and educational purposes only and does not constitute professional medical advice. Patients should not use the information presented on this page for diagnosing a health-related issue or disease. Before taking any medication or supplements, patients should always consult a physician or qualified healthcare professional for medical advice or information about whether a drug is safe, appropriate or effective.
