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(Triamterene / Hydrochlorothiazide)
Prescription required. Can not be split. Product of Canada. Shipped from Canada.
Dyazide (triamterene/hydrochlorothiazide) is generally used to treat high blood pressure. Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems. This medication is a combination of two "water pills" (diuretics): triamterene and hydrochlorothiazide.
The combination of these two water pills is used by people who have developed or are currently at risk for having low potassium levels on hydrochlorothiazide alone. This medication can cause you to make more urine, which helps your body get rid of extra salt and water. Dyazide (triamterene/hydrochlorothiazide) can also reduce swelling caused by extra fluid in the body (edema) related to conditions like heart failure, liver disease, or kidney disease.
To comply with Canadian International Pharmacy Association regulations you are permitted to order a 3-month supply or the closest package size available based on your personal prescription. read more
Here are general precautions when taking Dyazide (Triamterene / Hydrochlorothiazide):
Category | Precaution |
General Precautions | Triamterene tends to conserve potassium and can cause hyperkalemia in the body, sometimes leading to cardiac irregularities. Use may aggravate electrolyte imbalances, so following up on routine labwork is important. It’s important to monitor kidney function before and after starting Dyazide. Individuals with a history of liver disease should use caution before starting Dyazide. Dyazide should be used with caution in patients with a history of kidney stones. |
Laboratory Tests | Normal adult blood potassium levels are 3.5 to 5.0 mEq/L. Dyazide's triamterene component can raise potassium levels, causing symptoms like nausea, diarrhea, muscle weakness, or chest pain. Elevated potassium levels are dangerous and require prompt medical attention. It’s important to continue to monitor lab values over time. |
Drug Interactions | Lithium: monitor serum levels due to increased risk of toxicity. NSAIDs: use caution due to the potential for acute renal failure. Additive effects can be seen with other blood pressure medications like ACE inhibitors, diuretics, anesthetics, and muscle relaxants. It’s important to avoid other medications that also increase potassium unless use is explicitly advised by a healthcare provider who is aware of all your medications. |
Drug & Laboratory Test Interactions | Interferes with fluorescent measurement of quinidine. |
Carcinogenesis & Mutagenesis | Increased incidence of hepatocellular neoplasia in mice at high doses. No mutagenic effects in bacterial studies. |
Pregnancy | No teratogenic effects were observed in animal studies, but safe use during pregnancy has not been firmly established. Use during pregnancy only if clearly needed, under the guidance of a healthcare professional. Crosses placental barrier. |
Nursing Mothers | Likely present in human milk. Use only if essential; patients are advised to stop nursing if Dyazide therapy is continued. |
Pediatric Use | Safety and effectiveness not established in pediatric patients. |
Here are general dosage requirements for Dyazide (Triamterene / Hydrochlorothiazide):
Scenario | Dosage Guidelines |
Usual Starting Dose (Alone) | Once daily, often recommended in the morning |
Combined with Diuretic/Antihypertensive | Initial lower dosage of each agent, then adjusted to patient's needs |
Maximum Daily Dosage | 37.5 mg / 25 mg |
Switching from Other Diuretics | Discontinue all potassium supplementation when switching to triamterene capsules |
Adding to Other Diuretic Therapy | Discontinue all potassium supplementation when adding triamterene capsules to existing diuretic therapy |
Common side effects include the following:
Dizziness
Elevated potassium levels
Nausea
Diarrhea
Fatigue
Muscle cramps
If you experience these side effects or feel that they are not resolving or becoming worse after several days, it’s important to talk with your healthcare provider.
In rare cases, the components of Dyazide have been associated with serious side effects. If you experience a skin rash, contact your healthcare provider immediately. In some cases, this may be a sign of an allergic reaction or a more serious skin condition known as Stevens-Johnson syndrome (SJS). Dyazide has also been associated with changes in vision, like blurry vision or tunnel vision.
Other common questions:
Triamterene is a drug used for the management and treatment of high blood pressure and edema (swelling due to excess fluid). It is in the potassium-sparing diuretics class of drugs.
The content on this page is for informational and educational purposes only and does not constitute professional medical advice. Patients should not use the information presented on this page for diagnosing a health-related issue or disease. Before taking any medication or supplements, patients should always consult a physician or qualified healthcare professional for medical advice or information about whether a drug is safe, appropriate or effective.
