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(Plecanatide)
Prescription required. Can not be split. Product of Canada. Shipped from Canada.
Trulance (Plecanatide) is a prescription oral medication used to treat chronic idiopathic constipation (CIC) and irritable bowel syndrome with constipation (IBS-C) in adults. It works by activating a specific enzyme in the intestines, resulting in increased fluid secretion and enhanced muscle contractions. This helps soften stools, improve bowel movement regularity, and ease constipation-related discomfort.
Trulance (Plecanatide) is taken once daily and is designed for long-term management of these conditions.
Trulance (Plecanatide) is prescribed to:
Treat chronic idiopathic constipation (CIC) in adults
Manage IBS-C symptoms by improving stool consistency and frequency
Reduce abdominal bloating, discomfort, and straining
Trulance (Plecanatide) is not a laxative and is not meant for immediate relief of occasional constipation.
To comply with Canadian International Pharmacy Association regulations you are permitted to order a 3-month supply or the closest package size available based on your personal prescription. read more
Use Trulance (Plecanatide) exactly as prescribed by your healthcare provider. Common instructions often include:
Take 1 tablet (3 mg) by mouth once daily
Can be taken with or without food
Swallow whole or:
Crush and mix with a spoonful of applesauce or water, then swallow the entire mixture immediately
Administer via nasogastric or gastric feeding tube if necessary
Do not save mixed doses for later use (mixing may affect the stability of the drug, and it may not be as effective), and do not exceed one dose per day.
Before starting Trulance (Plecanatide), tell your doctor if you:
Have or suspect an intestinal blockage
Have a history of severe dehydration (always important, but of particular concern in pediatric patients)
Are pregnant, trying to conceive, or breastfeeding
Do NOT use Trulance (Plecanatide) if you:
Are allergic to plecanatide or any of its ingredients
Have a known bowel obstruction
Are under 6 years old (risk of severe dehydration)
Are under 18 years old, unless directed by a specialist (e.g., gastroenterologist)
No specific dietary restrictions are required
Staying hydrated and following a fiber-rich diet may help support regular bowel movements
If you miss a dose:
Take it as soon as you remember
If it's almost time for your next scheduled dose, skip the missed dose
Do not double up on doses
Try to take Trulance at the same time each day to build consistency.
Diarrhea (most common)
Abdominal bloating
Gas or cramping
Severe or prolonged diarrhea (increasing the risk of dehydration and potentially dangerous electrolyte imbalances)
Signs of allergic reaction:
Rash or hives
Swelling of face, lips, tongue, or throat
Difficulty breathing
Call your healthcare provider immediately if symptoms do not improve or if diarrhea becomes severe.
Report side effects to the FDA at 1-800-FDA-1088.
Store at room temperature (away from moisture and heat)
Keep tablets in the original bottle or blister pack until use
You may remove the packing coil from the bottle, but leave the moisture-absorbing packet
Keep out of reach of children and pets
Do not flush unused tablets—ask your pharmacist about safe disposal or local drug take-back programs.
Do not share Trulance (Plecanatide) with others
Trulance (Plecanatide) is contraindicated in children under 6 and is not recommended for anyone under 18
Avoid starting, stopping, or combining Trulance with other medications without consulting your doctor
Let your doctor know about all medications, including:
Prescription and over-the-counter drugs
Vitamins, supplements, and herbal remedies
If overdose is suspected, contact Poison Control at 1-800-222-1222 in the United States or 1-844-764-7669 in Canada, or seek emergency help right away.
The content on this page is for informational and educational purposes only and does not constitute professional medical advice. Patients should not use the information presented on this page for diagnosing a health-related issue or disease. Before taking any medication or supplements, patients should always consult a physician or qualified healthcare professional for medical advice or information about whether a drug is safe, appropriate or effective.
