Before taking ivabradine,
tell your doctor and pharmacist if you are allergic to ivabradine, any other medications, or any of the ingredients in ivabradine tablets. Ask your pharmacist or check the Medication Guide for a list of the ingredients.
tell your doctor if you are taking certain antibiotics such as clarithromycin (Biaxin, in Prevpac) and telithromycin (Ketek), certain antifungals such as itraconazole (Onmel, Sporanox), certain HIV protease inhibitors such as nelfinavir (Viracept), and nefazodone. Your doctor will probably tell you not to take ivabradine if you are taking one or more of these medications.
tell your doctor and pharmacist what other prescription and nonprescription medications, vitamins, and nutritional supplements you are taking or plan to take. Be sure to mention any of the following: amiodarone (Cordarone, Nexterone, Pacerone); beta blockers such as atenolol (Tenormin, in Tenoretic), carteolol, labetalol (Trandate), metoprolol (Lopressor, Toprol XL, in Dutoprol), nadolol (Corgard, Corzide), propranolol (Inderal, InnoPran XL, Hemangeol, in Inderide),sotalol (Betapace, Sorine, Sotylize), and timolol; digoxin (Lanoxin); diltiazem (Cardizem, Cartia, Tiazac, others); phenobarbital; phenytoin (Dilantin, Phenytek); rifampin (Rifadin, Rifamate, Rifater, Rimactane); and verapamil (Calan, Verelan, in Tarka). Your doctor may need to change the doses of your medications or monitor you carefully for side effects. Many other medications may also interact with ivabradine, so be sure to tell your doctor about all the medications you are taking, even those that do not appear on this list.
tell your doctor what herbal products you are taking, especially St. John's wort.
tell your doctor if you have an irregular or slow heartbeat, low blood pressure, a pacemaker, symptoms of heart failure that recently worsened, or liver disease. Your doctor will probably tell you not to take ivabradine.
tell your doctor if you have or have ever had any other heart problems.
tell your doctor if you are pregnant or plan to become pregnant. You should not become pregnant while you are taking ivabradine. Talk to your doctor about birth control methods that you can use during your treatment. If you become pregnant while taking ivabradine call your doctor.
you should know that ivabradine may affect your vision, especially when the brightness of the light around you changes. This may include seeing bright spots, bright circles around lights, bright colored lights, seeing double, and other unusual problems with your vision. These vision problems are most common when you first start taking ivabradine and they usually go away after a few months of treatment with this medication. Do not drive a car, especially at night, or operate machinery until you know how this medication affects you.