Xeljanz (Tofacitinib Citrate )
Prescription required. Can not be split. Product of Australia. Shipped from Australia.
To comply with Canadian International Pharmacy Association regulations you are permitted to order a 3-month supply or the closest package size available based on your personal prescription. read more
Tofacitinib Citrate Information
(toe'' fa sye' ti nib)Taking tofacitinib may decrease your ability to fight infection and increase the risk that you will get a serious infection, including severe fungal, bacterial, or viral infections that spread through the body. These infections may need to be treated in a hospital and may cause death. Tell your doctor if you often get any type of infection or if you think you may have any type of infection now. This includes minor infections (such as open cuts or sores), infections that come and go (such as cold sores), and chronic infections that do not go away. Also tell your doctor if you have or have ever had diabetes, human immunodeficiency virus (HIV), acquired immunodeficiency syndrome (AIDS), a lung disease, or any other condition that affects your immune system. You should also tell your doctor if you live or have ever lived in areas such as the Ohio or Mississippi river valleys where severe fungal infections are more common. Ask your doctor if you are not sure if these infections are common in your area. Tell your doctor if you are taking medications that decrease the activity of the immune system such as the following: abatacept (Orencia); adalimumab (Humira); anakinra (Kineret); azathioprine (Azasan, Imuran); certolizumab (Cimzia); cyclosporine (Gengraf, Neoral, Sandimmune); etanercept (Enbrel); golimumab (Simponi); infliximab (Remicade); methotrexate (Otrexup, Rasuvo, Trexall); rituximab (Rituxan); steroids including dexamethasone, methylprednisolone (Medrol), prednisolone (Prelone), and prednisone (Rayos); tacrolimus (Astagraf, Envarsus XR, Prograf); and tocilizumab (Actemra). Your doctor will monitor you for signs of infection during and after your treatment. If you have any of the following symptoms before you begin your treatment or if you experience any of the following symptoms during or shortly after your treatment, call your doctor immediately: fever; sweating; chills; muscle aches; painful or difficult swallowing; cough; shortness of breath; weight loss; warm, red, or painful skin; painful rash; headache, sensitivity to light, neck stiffness, confusion; frequent, painful, or burning feeling during urination; stomach pain; diarrhea; or excessive tiredness. You may already be infected with tuberculosis (TB; a serious lung infection) but not have any symptoms of the disease. In this case, using tofacitinib may make your infection more serious and cause you to develop symptoms. Your doctor will perform a skin test to see if you have an inactive TB infection before you begin your treatment with tofacitinib. If necessary, your doctor will give you medication to treat this infection before you start using tofacitinib. Tell your doctor if you have or have ever had TB, if you have lived in or visited a country where TB is common, or if you have been around someone who has TB. If you have any of the following symptoms of TB, or if you develop any of these symptoms during your treatment, call your doctor immediately: cough, coughing up bloody mucus, weight loss, loss of muscle tone, or fever. Taking tofacitinib in larger than recommended doses may cause serious or life-threatening heart problems during your treatment. Tell your doctor if you are 50 years of age or older or if you smoke, and if you have high cholesterol, high blood pressure, or diabetes. Take tofacitinib exactly as directed. Do not take more of it or take it more often than prescribed by your doctor. Taking tofacitinib may increase the risk that you will develop a lymphoma (cancer that begins in the blood cells that fight infection) or other types of cancers, including skin cancer. Some people who took tofacitinib with other medications after they had a kidney transplant developed a condition that caused their bodies to produce too many white blood cells. Tell your doctor if you have or have ever had any type of cancer or have had a kidney transplant. Taking tofacitinib in larger than recommended doses may increase the risk of life-threatening blood clots. Tell your doctor if you are 50 years of age or older and are at risk of heart or blood vessel disease. Also, tell your doctor if you have ever had a blood clot in your legs, arms, or lungs, or in the arteries. Take tofacitinib exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor. If you experience any of the following symptoms stop taking tofacitinib and call your doctor right away: sudden shortness of breath or difficulty breathing, chest pain, swelling of a leg or arm, leg pain, redness, discoloration, or warmth in the legs or arms.
Before taking tofacitinib,
- tell your doctor and pharmacist if you are allergic to tofacitinib, any other medications, or any of the ingredients in tofacitinib tablets or extended release tablets. Ask your pharmacist or check the Medication Guide for a list of the ingredients.
- tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, and nutritional supplements you are taking or plan to take. Be sure to mention the medications listed in the IMPORTANT WARNING section and any of the following: certain antifungal medications such as fluconazole (Diflucan), itraconazole (Onmel, Sporanox), and ketoconazole; aspirin and other nonsteroidal anti-inflammatory medications (NSAIDs) such as ibuprofen (Advil, Motrin) and naproxen (Naprosyn, Aleve); carbamazepine (Carbatrol, Tegretol, Equetro, others); clarithromycin (Biaxin, in Prevpac); certain medications for HIV including indinavir (Crixivan), nelfinavir (Viracept), and ritonavir (Norvir, in Kaletra); nefazodone; phenobarbital; phenytoin (Dilantin, Phenytek); rifabutin (Mycobutin); and rifampin (Rifadin, Rimactane, in Rifamate, in Rifater). Your doctor may need to change the doses of your medications or monitor you carefully for side effects.
- tell your doctor what herbal products you are taking, especially St. John's wort.
- tell your doctor if you have stomach pain that has not been diagnosed and if you have or have ever had ulcers (sores in the lining of your stomach or intestine), diverticulitis (swelling of the lining of the large intestine), liver disease including hepatitis B or hepatitis C, cancer, anemia (a lower than normal number of red blood cells), dialysis (medical treatment to clean the blood when the kidneys are not working properly), or kidney disease. If you are taking the extended-release tablets, tell your doctor if you have a narrowing or blockage of your digestive system.
- tell your doctor if you are pregnant or plan to become pregnant. You should not become pregnant while you are taking tofacitinib. If you become pregnant while taking tofacitinib, call your doctor.
- tell your doctor if you are breastfeeding. Do not breastfeed while you are taking tofacitinib and for at least 18 hours after the final dose of the tablet or for at least 36 hours after the final dose of the extended-release tablet.
- you should know that this medication may decrease fertility in women. Talk to your doctor about the risks of taking tofacitinib.
- tell your doctor if you have recently received or are scheduled to receive any vaccinations. If you need any vaccinations, you may have to receive the vaccinations and then wait some time before beginning your treatment with tofacitinib. Do not have any vaccinations during your treatment without talking to your doctor.
- stuffy or runny nose
- hives, swelling of face, eyes, lips, or throat, difficulty swallowing or breathing
- stomach pain, especially if it comes along with fever and diarrhea or constipation
- yellowing of the skin or eyes
- loss of appetite
- dark urine
- clay-colored bowel movements
- pale skin
- shortness of breath