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Colcrys (colchicine) is a prescription medication used to prevent and treat gout attacks, a painful form of inflammatory arthritis caused by the buildup of uric acid crystals in the joints. It is also FDA-approved to treat familial Mediterranean fever (FMF), a rare genetic condition that causes recurring fevers and inflammation in the abdomen, chest, or joints.
Colchicine works by reducing inflammation and decreasing the accumulation of uric acid, which helps relieve pain and swelling during a flare. It does not cure gout or FMF, but it can significantly reduce the frequency and severity of attacks. This medication may also be used off-label for other inflammatory conditions, as directed by your healthcare provider.
Key Takeaways
Availability: Colcrys (colchicine) is available by prescription through licensed online pharmacies and telehealth providers, including PlanetDrugsDirect, DrugMart, and PlushCare. Prices start as low as $23.40 for 30 tablets of the generic equivalent (0.6 mg strength) from PlanetDrugsDirect.
How It Works: Colchicine reduces inflammation and prevents the buildup of uric acid crystals in the joints, making it effective in treating and preventing gout flares and managing familial Mediterranean fever (FMF).
Common Side Effects: The most frequent side effects include nausea, vomiting, stomach pain, and diarrhea. Serious reactions—such as muscle weakness, numbness, or signs of toxicity—may occur, especially in cases of overdose or when combined with interacting medications. Immediate medical attention is required for severe symptoms.
3 Places to Buy Colcrys (Colchicine) Online
Colcrys (colchicine) is a prescription medication used to treat and prevent gout flares and manage familial Mediterranean fever (FMF). It works by reducing inflammation and preventing uric acid crystal buildup in joints. Colcrys is typically prescribed in 0.6 mg tablet form and may be taken at the first sign of a gout flare or used daily for prevention.
Price Comparison – Generic Equivalent Colchicine (30-Tablet Adjusted Price)
Provider | Adjusted Price (30 Tablets) | Dosage | Prescription Required | Link |
PlanetDrugsDirect | $23.40 | 0.6 mg | Yes | |
DrugMart | $23.44 | 0.6 mg | Yes | |
PlushCare | Varies (includes telehealth) | Varies | Yes |
Prices updated as of April 5, 2025. Actual costs may vary based on shipping, location, and availability.
Where to Buy Generic Equivalent of Colcrys Online
1. PlanetDrugsDirect
PlanetDrugsDirect is a CIPA-certified international pharmacy that offers bulk pricing on generic equivalent colchicine with international shipping.
Adjusted Price: $23.40 for 30 tablets
Strength: 0.6 mg
Prescription Required: Yes
2. DrugMart
DrugMart is a CIPA-certified international pharmacy that provides competitively priced generic equivalent colchicine with direct U.S. delivery and no telehealth consultation required.
Adjusted Price: $23.44 for 30 tablets
Strength: 0.6 mg
Prescription Required: Yes
3. PlushCare
Telehealth platform offering colchicine prescriptions through licensed physicians. Pricing includes medical consultation and may vary depending on your provider and pharmacy.
Price: Varies (includes telehealth visit)
Strength: Varies
Prescription Required: Yes
What is Colcrys (Colchicine)?
Colcrys (colchicine) is a prescription medication used to treat and prevent gout attacks in adults and to manage Familial Mediterranean Fever (FMF) in adults and children aged 4 years and older. It works by affecting the body’s response to uric acid crystal buildup, reducing inflammation, swelling, and pain during gout flares. Though originally developed before modern FDA drug approval processes, Colcrys became the first FDA-approved brand of colchicine in 2009.
Colchicine is not a cure for gout or FMF and will not prevent disease progression. It should only be used for the conditions it’s prescribed for and not as a general pain reliever. Off-label uses, such as for Behçet’s syndrome, may be considered under a physician’s guidance.
Warnings
Colcrys (colchicine) can interact dangerously with other medications, especially in people with liver or kidney disease. Always tell your doctor about every medication you’re taking.
Do not use Colcrys if you:
Are allergic to colchicine
Tell your doctor before use if you have:
Liver or kidney disease
Heart disease
Ulcers or gastrointestinal disorders (e.g., Crohn’s disease, ulcerative colitis)
A history of intestinal bleeding
Drug Interactions
Colcrys (colchicine) may interact with:
Clarithromycin, telithromycin
Cyclosporine
Antifungals (itraconazole, ketoconazole)
HIV medications (ritonavir, indinavir, saquinavir, etc.)
Nefazodone
Cholesterol-lowering drugs
Digoxin
Pregnancy and Breastfeeding
It is not known whether Colcrys can harm an unborn baby—consult your doctor if pregnant.
Colchicine passes into breast milk and may harm a nursing infant. Let your doctor know if you are breastfeeding.
How to Take Colcrys (Colchicine)
Take exactly as prescribed. Do not exceed your recommended dose.
Can be taken with or without food.
For gout flares: take Colcrys at the first sign of symptoms for best results.
A second (lower) dose may be taken an hour later, if instructed by your doctor.
Dosing varies depending on the condition being treated (e.g., gout vs. FMF).
Continue taking the medication even if symptoms improve—do not stop without consulting your doctor.
What to Avoid
Avoid grapefruit and grapefruit juice—they may increase colchicine levels and the risk of side effects.
Missed Dose or Overdose
Missed Dose: Take as soon as you remember. Skip if it's almost time for your next dose—do not double up.
Overdose: Seek emergency help or contact Poison Control at 1-800-222-1222. An overdose of colchicine can be fatal.
Overdose Symptoms Include:
Severe nausea, vomiting, or diarrhea
Weak pulse, fainting, or slow heart rate
Muscle weakness
Numbness or tingling
Little or no urination
Pale or gray lips, tongue, or hands
Weak or shallow breathing
Side Effects
Serious and common side effects include some of the following:
Serious Side Effects (Call your doctor immediately):
Muscle pain or weakness
Numbness or tingling in extremities
Pale or gray lips, tongue, or hands
Severe or prolonged vomiting or diarrhea
Fever, chills, flu-like symptoms
Easy bruising, unusual bleeding, or extreme fatigue
Common Side Effects:
Nausea
Vomiting
Stomach pain
Diarrhea
This is not a complete list of side effects. Contact your doctor with any concerns, and report serious reactions to the FDA at 1-800-FDA-1088.
Rely on PlanetDrugsDirect.com to Buy Online Colcrys (Colchicine)
As a trusted prescription referral service, we offer important benefits whenever you order online. Each of our partner pharmacies and/or government-approved dispensaries is committed to providing the best experience possible of any online prescription referral service on the internet. We offer:
Low prices
Quick turn-around times
Generic and brand-name medications
Unparalleled customer service
Sources
U.S. Food and Drug Administration. (2014). Colcrys (colchicine, USP) tablets: Prescribing information. Retrieved from https://www.accessdata.fda.gov/drugsatfda_docs/label/2014/022352s017lbl.pdf
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