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Cytotec (Misoprostol) is a prescription oral medication most commonly used to prevent stomach ulcers in patients taking NSAIDs long-term. It is also used off-label in gynecological settings for cervical ripening and labor induction, and in combination with mifepristone for medical abortion. Misoprostol works by protecting the stomach lining and reducing acid secretion.
Cytotec is taken multiple times daily depending on its clinical use and dosage. While the medication is widely prescribed, it can be costly without insurance, especially in the United States. Fortunately, international online pharmacies offer drastically lower prices.
Key Takeaways
Online Pharmacies Offer Cytotec for as Low as $25–$30 per Month: CIPA-certified pharmacies like Planet Drugs Direct and DrugMart sell 200mcg misoprostol tablets at a fraction of U.S. retail prices—offering up to 90% savings when compared to Amazon or chain pharmacies.
U.S. Pharmacy Prices Exceed $190–$370+ per Fill Without Insurance: A 30-tablet supply of Cytotec at U.S. retailers like CVS, Walgreens, and Amazon can cost $187 to over $370, especially for lower-dose 100mcg tablets, making it cost-prohibitive for many without coverage.
No Copay Card or Manufacturer Discounts Exist for Cytotec: Unlike many chronic condition medications, Cytotec has no active copay assistance or trial offer programs in the U.S. Patients must rely on generic versions and international pharmacy access to reduce out-of-pocket expenses.
Cheapest Online Pharmacies for Cytotec (Misoprostol)
Here are the cheapest online pharmacies where you can purchase Cytotec (Misoprostol) and get it shipped safely, right to your door.
Pharmacy | Prescription Required | Price Per 30 Tablets (Estimated) | Milligram | Website |
Planet Drugs Direct | Yes | $25.58 | 200mcg | |
DrugMart | Yes | $29.06 | 200mcg | |
Amazon Pharmacy | Yes | $370.67 | 100mcg |
Prices as of April 30, 2025. Prices are subject to change based on quantity, milligram, and other details regarding your prescription needs.
U.S. Retail Prices for Cytotec (Misoprostol)
Retail pharmacy prices remain high for Cytotec (Misoprostol). Based on recent April 2025 data, the average cost for a 30-day supply at major local pharmacies includes:
CVS Pharmacy: $201.73
Walgreens: $195.36
Walmart: $195.75
Jewel-Osco: $187.25
Ready to purchase your medication for up to 80% off? Visit Planet Drugs Direct.
How to Save on Cytotec (Misoprostol)
Here are some ways to save on Cytotec (Misoprostol):
1. Use a CIPA-Certified Online Pharmacy
If you’re paying out-of-pocket or your local pharmacy quotes an unaffordable price, consider ordering from a CIPA-certified international pharmacy. These pharmacies are licensed, vetted, and ship FDA-approved generics from regulated countries.
Planet Drugs Direct and DrugMart both offer up to 90% savings compared to Amazon Pharmacy.
A valid U.S. prescription is required to order.
Delivery typically takes 2–3 weeks.
2. Ask for the Generic Version: Misoprostol
Always request the generic version of Cytotec (misoprostol), as there is no longer a U.S.-exclusive branded option widely available. Generic misoprostol is chemically identical and significantly less expensive when sourced internationally.
3. Compare Dosages Carefully
Amazon Pharmacy lists 100mcg tablets, while international pharmacies more commonly stock 200mcg tablets—often the preferred dose for gastric ulcer prevention. This may help reduce the number of tablets needed, further lowering cost.
Common Questions About Cytotec (Misoprostol)
Common questions and answers:
1. Is Cytotec covered by Medicare or insurance?
Cytotec is rarely covered under Medicare Part D or commercial insurance unless explicitly prescribed for ulcer prevention. Coverage for off-label gynecological uses is generally denied.
2. How much would I expect to pay if I have no insurance?
Without insurance, U.S. pharmacy prices exceed $700 for just 60 tablets. By comparison, international pharmacies charge as little as $25–$30 for the same or higher strength, making them the most cost-effective option.
3. How long will I need to take Cytotec, and how much will that cost?
The duration depends entirely on its use case:
For NSAID-related ulcer prevention: Cytotec is typically taken long-term, with an average cost of $25–$30/month using international pharmacies.
For reproductive care: Dosage is short-term and variable, but even one-time uses from U.S. pharmacies may cost hundreds. Using international sources may lower the cost to under $50 total with a prescription.
Rely on PlanetDrugsDirect.com to Buy Online Cytotec
As a trusted prescription referral service, we offer important benefits whenever you order online. Each of our partner pharmacies and/or government-approved dispensaries is committed to providing the best experience possible of any online prescription referral service on the internet. We offer:
Low prices
Quick turn-around times
Generic and brand-name medications
Unparalleled customer service
Sources
G.D. Searle & Co. (2002, February). Cytotec (misoprostol) tablets: Prescribing information. U.S. Food and Drug Administration. Retrieved from https://www.accessdata.fda.gov/drugsatfda_docs/label/2002/19268slr037.pdf
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