
As CVS Health enters the final phase of its multi-year retail overhaul, the company continues to close hundreds of stores in 2025—building on the nearly 900 shuttered since 2021. The closures reflect CVS’s strategy to reformat its nationwide footprint amid changing consumer behavior, rising digital healthcare adoption, and the need for greater operational efficiency.
In rural states like Arizona, where access to pharmacies is already limited, these shutdowns raise concerns about healthcare access in underserved communities. To help fill the gap, online and mail-order pharmacies have become critical alternatives, offering delivery, virtual care, and cost savings for both insured and uninsured patients alike.
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Key Takeaways
CVS Store Closures Continue Into 2025: CVS is closing up to 270 more locations this year as part of its effort to modernize its store formats and focus on better-performing areas. This builds on the 900 closures completed between 2022 and 2024.
Shift to Smaller, Health-Centered Models: New CVS locations will include HealthHUBs, smaller-format pharmacies, and stores with built-in primary care services, reflecting a pivot toward localized and preventive care access.
Digital Care Is Replacing Brick-and-Mortar Visits: CVS’s emphasis on telehealth, online prescription management, and delivery reflects a national trend toward digital-first healthcare, especially among Medicare patients, seniors, and tech-savvy consumers.
Industry-Wide Consolidation: CVS is not alone—Walgreens is closing 1,200 stores, and Rite Aid is undergoing bankruptcy-driven downsizing. The entire pharmacy retail sector is calibration to match evolving consumer needs and financial realities.
CVS Store Closures as of 2024 and into 2025
The list may be ongoing into 2025 as CVS continues to close up to 270 locations this year:
State | City | Address |
Alabama | Bessemer | 2901 Morgan Rd. |
Alabama | Birmingham | 3303 Clairmont Ave. |
California | San Francisco | 499 Haight St. |
California | Sacramento | 1701 K St. |
Florida | Tallahassee | 3090 S. Monroe St. |
Florida | Orlando | 13300 E. Colonial Dr. |
Florida | Orlando | 2201 Edgewater Dr. |
Georgia | Atlanta | 439 Highland Blvd. |
Illinois | Chicago (multiple) | 11 total locations incl. 8639 S. Cicero Ave. |
Iowa | Ames | 2420 Lincoln Way |
Iowa | Des Moines | 215 Euclid Ave. |
Massachusetts | Boston | 55 Summer St. |
Michigan | Roseville | 28774 Gratiot Ave. |
Michigan | St. Clair Shores | 27700 Harper Ave. |
Missouri | Kansas City | 2435 Independence Ave. |
Missouri | St. Louis | 9433 Manchester Rd. |
New York | New York City & Albany | Multiple locations |
North Carolina | Winston-Salem | 201 W. 4th St. |
Ohio | Cleveland | 10825 Kinsman Rd. |
Pennsylvania | Plymouth | 125 E. Main St. |
Virginia | Fairfax | 10390 Willard Way |
Washington, D.C. | Multiple Locations | Including 400 Massachusetts Ave. NW |
Connecticut | Hartford | 690 Wethersfield Ave, 777 Main Street |
Indiana | Indianapolis | 9550 Allisonville Rd, 5110 E 38th St |
Minnesota | Coon Rapids, Duluth, etc | Multiple |
Texas | Dallas, Fort Worth, etc | Multiple |
Maryland | Baltimore, Gaithersburg | Multiple |
Arizona | Phoenix, Peoria | Multiple |
Nevada | Las Vegas | 2735 S. Maryland Parkway |
List updated as of May 19th, 2025.
Latest CVS Store Closures
Based on our research, here are the latest CVS stores to close in 2025:
State | City | Address |
Alabama | Bessemer | 2901 Morgan Rd. |
| Birmingham | 3303 Clairmont Ave. |
California | San Francisco | 499 Haight St. |
| Sacramento | 1701 K St. |
Florida | Tallahassee | 3090 S. Monroe St. |
| Orlando | 13300 E. Colonial Dr. |
| Orlando | 2201 Edgewater Dr. |
Georgia | Atlanta | 439 Highland Blvd. |
Illinois | Chicago | 8639 S. Cicero Ave. |
| Chicago | 401 W. Armitage Ave. |
| Highland Park | 2000 Skokie Valley Rd. |
Iowa | Ames | 2420 Lincoln Way |
| Des Moines | 215 Euclid Ave. |
Massachusetts | Boston | 55 Summer St. |
Michigan | Roseville | 28774 Gratiot Ave. |
| St. Clair Shores | 27700 Harper Ave. |
Missouri | Kansas City | 2435 Independence Ave. |
| Kansas City | 4531 Troost Ave. |
| Saint Louis | 9433 Manchester Rd. |
New York | North Tonawanda | 955 Payne Ave. |
| Albany | 153 Central Ave. |
| Albany | 1026 Madison Ave. |
| New York | 1241 Lexington Ave. |
| Staten Island | 1654 Richmond Ave. |
North Carolina | Winston-Salem | 201 W. 4th St. |
Ohio | Cleveland | 10825 Kinsman Rd. |
Pennsylvania | Plymouth | 125 E. Main St. |
Virginia | Fairfax | 10390 Willard Way |
Washington, D.C. | Washington, D.C. | 1117 10th St. NW |
|
| 1100 4th St. SW |
|
| 400 Massachusetts Ave. NW |
|
| 1515 New York Ave. NE |
|
| 4500 Wisconsin Ave. NW |
|
| 7828 Georgia Ave. NW |
List updated as of May 19th, 2025.
Why CVS Is Closing Stores in 2025
CVS began this store reduction initiative in 2021 with a three-year plan to close 900 underperforming stores. The company is finalizing that strategy in 2025 with hundreds more closures. These efforts aim to optimize their footprint and strengthen stores that remain open.
Other reasons include the following:
1. Low Foot Traffic and Overlap
Many of the stores being closed are either located in low-traffic areas or near other high-performing CVS locations. This redundancy allowed CVS to consolidate without sacrificing coverage.
2. Rise of Digital Healthcare
With the expansion of CVS’s digital tools—such as online prescription management, mail-order delivery, and telehealth services—fewer customers rely on brick-and-mortar visits for basic pharmacy needs.
3. Shift Toward Smaller-Format Stores
CVS plans to open “a dozen or more” smaller pharmacy locations across the country in 2025. These stores are designed to fit better into local neighborhoods, offering quicker access to medications, vaccinations, and pharmacist-led care.
4. Growth of HealthHub and Primary Care Services
Some new CVS locations will feature enhanced HealthHub formats or embedded primary care services. These models focus on wellness, chronic condition management, and preventive services—moving beyond traditional retail.
5. Community-Focused Customization
Rather than taking a one-size-fits-all approach, CVS is building a more customized store network. Stores are being redesigned to address the specific healthcare needs of each community, particularly in underserved areas.
6. Response to Consumer Buying Shifts
CVS executives, including CEO Karen Lynch, have pointed to changes in consumer behavior—especially since the pandemic—as a key factor behind the closures. The emphasis is now on delivering services where and how consumers prefer them.
7. Financial Impact and Recovery Strategy
The initial wave of closures cost CVS approximately $1 billion in late 2021. However, the company believes this upfront loss is a worthwhile investment in a stronger, more efficient future—with better-performing locations and improved digital reach.
8. Industry-Wide Trend
CVS isn’t alone. Competitors like Walgreens and Rite Aid are also shuttering hundreds of locations. Walgreens plans to close 1,200 stores as part of its own cost-cutting initiative, while Rite Aid is downsizing amid bankruptcy proceedings.
Other Options to Purchase Medications Instead of CVS
With CVS continuing to close stores across the U.S.—including in Arizona, California, and Washington, D.C.—patients in affected areas may need reliable alternatives for their prescriptions. Fortunately, several online and mail-order pharmacies offer affordable, accessible, and secure options.
Among them, Planet Drugs Direct stands out as the top choice for out-of-pocket savings, especially for the uninsured or those with chronic conditions requiring long-term medication.
Provider | Key Features | Best For | Insurance Accepted |
CIPA-certified international pharmacy; up to 80% off U.S. retail prices; ships from abroad | Long-term meds, out-of-pocket savings | No | |
Wide selection of brand/generic drugs; Prime discounts; integrates with insurance | General prescriptions with insurance | Yes | |
Meds pre-sorted by day/time; auto-refills; delivered monthly | Chronic care and senior patients | Yes | |
Online refills and delivery; some drugs require in-store pickup | Insurance users with common prescriptions | Yes | |
Home delivery of maintenance and specialty drugs; includes support services | Employer or Medicare-linked plans | Yes | |
Virtual consults for hair loss, birth control, ED, mental health | Discreet care for men’s/women’s health | No | |
U.S.-licensed; low-cost preventive and chronic condition meds | Budget-conscious chronic care patients | Limited | |
Telehealth + prescriptions for anxiety, depression, and birth control | Fast care for specific conditions | No | |
Women’s health (STIs, birth control, migraines); regular delivery cycles | Ongoing women’s health needs | No | |
Drug price comparison and coupons for local/online pharmacies | Cash payers looking for the best deal | No (cash pricing) | |
Based in India; international shipping; large selection | Non-urgent medications | No |
List updated as of May 19th, 2025.
Why Choose Planet Drugs Direct?
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Great for Long-Term Needs: Ships large quantities (e.g., 90 or 100 tablets) for chronic conditions.
Available Nationwide: Delivers to all 50 U.S. states, including rural and underserved ZIP codes.
Transparent Pricing: No hidden fees, no insurance complexities—just consistent low-cost prescriptions.
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