Latest CVS Store Closings (Updated May 2025)

Matthew Sommers Medically reviewed by Matthew Sommers on

CVS Closures Leave Gaps in Care

As CVS Health enters the final phase of its multi-year retail overhaul, the company continues to close hundreds of stores in 2025—building on the nearly 900 shuttered since 2021. The closures reflect CVS’s strategy to reformat its nationwide footprint amid changing consumer behavior, rising digital healthcare adoption, and the need for greater operational efficiency. 

In rural states like Arizona, where access to pharmacies is already limited, these shutdowns raise concerns about healthcare access in underserved communities. To help fill the gap, online and mail-order pharmacies have become critical alternatives, offering delivery, virtual care, and cost savings for both insured and uninsured patients alike.

Looking to fill your prescription? Use Planet Drugs Direct to get up 80% off U.S retail prices and get your medication shipped anywhere in the United States.

Key Takeaways

  • CVS Store Closures Continue Into 2025: CVS is closing up to 270 more locations this year as part of its effort to modernize its store formats and focus on better-performing areas. This builds on the 900 closures completed between 2022 and 2024.

  • Shift to Smaller, Health-Centered Models: New CVS locations will include HealthHUBs, smaller-format pharmacies, and stores with built-in primary care services, reflecting a pivot toward localized and preventive care access.

  • Digital Care Is Replacing Brick-and-Mortar Visits: CVS’s emphasis on telehealth, online prescription management, and delivery reflects a national trend toward digital-first healthcare, especially among Medicare patients, seniors, and tech-savvy consumers.

  • Industry-Wide Consolidation: CVS is not alone—Walgreens is closing 1,200 stores, and Rite Aid is undergoing bankruptcy-driven downsizing. The entire pharmacy retail sector is calibration to match evolving consumer needs and financial realities.

CVS Store Closures as of 2024 and into 2025

The list may be ongoing into 2025 as CVS continues to close up to 270 locations this year:

State

City

Address

Alabama

Bessemer

2901 Morgan Rd.

Alabama

Birmingham

3303 Clairmont Ave.

California

San Francisco

499 Haight St.

California

Sacramento

1701 K St.

Florida

Tallahassee

3090 S. Monroe St.

Florida

Orlando

13300 E. Colonial Dr.

Florida

Orlando

2201 Edgewater Dr.

Georgia

Atlanta

439 Highland Blvd.

Illinois

Chicago (multiple)

11 total locations incl. 8639 S. Cicero Ave.

Iowa

Ames

2420 Lincoln Way

Iowa

Des Moines

215 Euclid Ave.

Massachusetts

Boston

55 Summer St.

Michigan

Roseville

28774 Gratiot Ave.

Michigan

St. Clair Shores

27700 Harper Ave.

Missouri

Kansas City

2435 Independence Ave.

Missouri

St. Louis

9433 Manchester Rd.

New York

New York City & Albany

Multiple locations

North Carolina

Winston-Salem

201 W. 4th St.

Ohio

Cleveland

10825 Kinsman Rd.

Pennsylvania

Plymouth

125 E. Main St.

Virginia

Fairfax

10390 Willard Way

Washington, D.C.

Multiple Locations

Including 400 Massachusetts Ave. NW

Connecticut

Hartford

690 Wethersfield Ave, 777 Main Street

Indiana

Indianapolis

9550 Allisonville Rd, 5110 E 38th St

Minnesota

Coon Rapids, Duluth, etc

Multiple

Texas

Dallas, Fort Worth, etc

Multiple

Maryland

Baltimore, Gaithersburg

Multiple

Arizona

Phoenix, Peoria

Multiple

Nevada

Las Vegas

2735 S. Maryland Parkway

List updated as of May 19th, 2025.

Latest CVS Store Closures

Based on our research, here are the latest CVS stores to close in 2025:

State

City

Address

Alabama

Bessemer

2901 Morgan Rd.

 

Birmingham

3303 Clairmont Ave.

California

San Francisco

499 Haight St.

 

Sacramento

1701 K St.

Florida

Tallahassee

3090 S. Monroe St.

 

Orlando

13300 E. Colonial Dr.

 

Orlando

2201 Edgewater Dr.

Georgia

Atlanta

439 Highland Blvd.

Illinois

Chicago

8639 S. Cicero Ave.

 

Chicago

401 W. Armitage Ave.

 

Highland Park

2000 Skokie Valley Rd.

Iowa

Ames

2420 Lincoln Way

 

Des Moines

215 Euclid Ave.

Massachusetts

Boston

55 Summer St.

Michigan

Roseville

28774 Gratiot Ave.

 

St. Clair Shores

27700 Harper Ave.

Missouri

Kansas City

2435 Independence Ave.

 

Kansas City

4531 Troost Ave.

 

Saint Louis

9433 Manchester Rd.

New York

North Tonawanda

955 Payne Ave.

 

Albany

153 Central Ave.

 

Albany

1026 Madison Ave.

 

New York

1241 Lexington Ave.

 

Staten Island

1654 Richmond Ave.

North Carolina

Winston-Salem

201 W. 4th St.

Ohio

Cleveland

10825 Kinsman Rd.

Pennsylvania

Plymouth

125 E. Main St.

Virginia

Fairfax

10390 Willard Way

Washington, D.C.

Washington, D.C.

1117 10th St. NW

 

 

1100 4th St. SW

 

 

400 Massachusetts Ave. NW

 

 

1515 New York Ave. NE

 

 

4500 Wisconsin Ave. NW

 

 

7828 Georgia Ave. NW

List updated as of May 19th, 2025.

Why CVS Is Closing Stores in 2025

CVS began this store reduction initiative in 2021 with a three-year plan to close 900 underperforming stores. The company is finalizing that strategy in 2025 with hundreds more closures. These efforts aim to optimize their footprint and strengthen stores that remain open.

Other reasons include the following:

1. Low Foot Traffic and Overlap

Many of the stores being closed are either located in low-traffic areas or near other high-performing CVS locations. This redundancy allowed CVS to consolidate without sacrificing coverage.

2. Rise of Digital Healthcare

With the expansion of CVS’s digital tools—such as online prescription management, mail-order delivery, and telehealth services—fewer customers rely on brick-and-mortar visits for basic pharmacy needs.

3. Shift Toward Smaller-Format Stores

CVS plans to open “a dozen or more” smaller pharmacy locations across the country in 2025. These stores are designed to fit better into local neighborhoods, offering quicker access to medications, vaccinations, and pharmacist-led care.

4. Growth of HealthHub and Primary Care Services

Some new CVS locations will feature enhanced HealthHub formats or embedded primary care services. These models focus on wellness, chronic condition management, and preventive services—moving beyond traditional retail.

5. Community-Focused Customization

Rather than taking a one-size-fits-all approach, CVS is building a more customized store network. Stores are being redesigned to address the specific healthcare needs of each community, particularly in underserved areas.

6. Response to Consumer Buying Shifts

CVS executives, including CEO Karen Lynch, have pointed to changes in consumer behavior—especially since the pandemic—as a key factor behind the closures. The emphasis is now on delivering services where and how consumers prefer them.

7. Financial Impact and Recovery Strategy

The initial wave of closures cost CVS approximately $1 billion in late 2021. However, the company believes this upfront loss is a worthwhile investment in a stronger, more efficient future—with better-performing locations and improved digital reach.

8. Industry-Wide Trend

CVS isn’t alone. Competitors like Walgreens and Rite Aid are also shuttering hundreds of locations. Walgreens plans to close 1,200 stores as part of its own cost-cutting initiative, while Rite Aid is downsizing amid bankruptcy proceedings.

Other Options to Purchase Medications Instead of CVS

With CVS continuing to close stores across the U.S.—including in Arizona, California, and Washington, D.C.—patients in affected areas may need reliable alternatives for their prescriptions. Fortunately, several online and mail-order pharmacies offer affordable, accessible, and secure options. 

Among them, Planet Drugs Direct stands out as the top choice for out-of-pocket savings, especially for the uninsured or those with chronic conditions requiring long-term medication.

Provider

Key Features

Best For

Insurance Accepted

Planet Drugs Direct

CIPA-certified international pharmacy; up to 80% off U.S. retail prices; ships from abroad

Long-term meds, out-of-pocket savings

No

Amazon Pharmacy

Wide selection of brand/generic drugs; Prime discounts; integrates with insurance

General prescriptions with insurance

Yes

PillPack by Amazon

Meds pre-sorted by day/time; auto-refills; delivered monthly

Chronic care and senior patients

Yes

CVS Pharmacy

Online refills and delivery; some drugs require in-store pickup

Insurance users with common prescriptions

Yes

Optum Rx

Home delivery of maintenance and specialty drugs; includes support services

Employer or Medicare-linked plans

Yes

Hims and Hers

Virtual consults for hair loss, birth control, ED, mental health

Discreet care for men’s/women’s health

No

HealthWarehouse

U.S.-licensed; low-cost preventive and chronic condition meds

Budget-conscious chronic care patients

Limited

Lemonaid Health

Telehealth + prescriptions for anxiety, depression, and birth control

Fast care for specific conditions

No

Nurx

Women’s health (STIs, birth control, migraines); regular delivery cycles

Ongoing women’s health needs

No

GoodRx

Drug price comparison and coupons for local/online pharmacies

Cash payers looking for the best deal

No (cash pricing)

Netmeds

Based in India; international shipping; large selection

Non-urgent medications

No

List updated as of May 19th, 2025.

Why Choose Planet Drugs Direct?

  • Massive Savings: Get up to 80% off U.S. retail prices—ideal for those without insurance.

  • CIPA-Certified Safety: Verified by the Canadian International Pharmacy Association for consumer protection.

  • Great for Long-Term Needs: Ships large quantities (e.g., 90 or 100 tablets) for chronic conditions.

  • Available Nationwide: Delivers to all 50 U.S. states, including rural and underserved ZIP codes.

  • Transparent Pricing: No hidden fees, no insurance complexities—just consistent low-cost prescriptions.

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The content on this page is for informational and educational purposes only and does not constitute professional medical advice. Patients should not use the information presented on this page for diagnosing a health-related issue or disease. Before taking any medication or supplements, patients should always consult a physician or qualified healthcare professional for medical advice or information about whether a drug is safe, appropriate or effective.