Medically reviewed by 
Trelegy Ellipta (Fluticasone Furoate/Umeclidinium/Vilanterol) is a prescription once-daily inhaler used for the long-term maintenance treatment of chronic obstructive pulmonary disease (COPD) and asthma. It combines three active ingredients: a corticosteroid (fluticasone furoate), a long-acting muscarinic antagonist (umeclidinium), and a long-acting beta2-agonist (vilanterol), providing broad-spectrum relief by reducing inflammation, relaxing airway muscles, and improving lung function.
While Trelegy Ellipta (Fluticasone Furoate/Umeclidinium/Vilanterol) is clinically effective, it can be expensive without insurance—retail prices in the U.S. range from $802 to $898 per inhaler.
Key Takeaways
CIPA-Certified Online Pharmacies Offer Major Savings: Verified international pharmacies like DrugMart and Planet Drugs Direct offer Trelegy Ellipta for as low as $192.99 per inhaler, saving over 75% compared to U.S. retail prices. Purchase from Planet Drugs Direct.
U.S. Pharmacies Charge $802 to $898 Without Insurance: Major pharmacies such as Walgreens, CVS, and Walmart list Trelegy Ellipta for between $802 and $898 per 30-day supply.
Trelegy Ellipta Is Covered by Most Medicare Part D Plans: Over 96% of Medicare plans cover Trelegy, although costs may vary based on your plan and coverage phase. There is no manufacturer savings card, but Medicare Advantage and Part D patients typically receive tiered copay support.
Cheapest Online Pharmacies for Trelegy Ellipta (Fluticasone Furoate/Umeclidinium/Vilanterol)
Below are the lowest international pharmacy prices for a 30-day inhaler of Trelegy Ellipta:
Pharmacy | Prescription Required | Price | Dosage | Website |
Planet Drugs Direct | Yes | $192.99 | 184mcg/55mcg/22mcg | |
DrugMart | Yes | $193.20 | 184mcg/55mcg/22mcg | |
Amazon Pharmacy | Yes | $628.70 | 100mcg/62.5mcg/25mcg |
Prices as of June 2, 2025. Pricing varies by pharmacy, location, and prescription.
U.S. Retail Prices for Trelegy Ellipta (Fluticasone Furoate/Umeclidinium/Vilanterol)
These are the current out-of-pocket prices for a single inhaler (30-day supply) at major U.S. pharmacies:
Pharmacy | Retail Price |
Meijer Pharmacy | $839.26 |
Aurora Pharmacy | $832.81 |
Mariano’s | $812.99 |
Capsule Pharmacy | $832.81 |
Jewel-Osco | $897.99 |
Walgreens | $857.46 |
Walgreens Specialty Pharmacy | $858.09 |
Walmart | $813.39 |
Walmart Neighborhood Market | $812.89 |
CVS Pharmacy | $802.01 |
Target (CVS) | $801.98 |
Costco | $831.96 |
Retail prices are for a 30-day supply. Prices may vary slightly depending on store and location.
How to Save on Trelegy Ellipta (Fluticasone Furoate/Umeclidinium/Vilanterol)
Here’s how to save on Trelegy Ellipta:
1. Use Medicare Part D or Medicare Advantage Coverage
Trelegy Ellipta is widely covered by Medicare, with over 96% of Medicare Part D plans including it on their formularies.
Coverage Phase Impacts Cost: Your copay or coinsurance will depend on whether you’re in the deductible, initial coverage, coverage gap ("donut hole"), or catastrophic phase.
No Prior Authorization Usually Required: Trelegy is commonly approved without needing additional paperwork.
Medicare Advantage Plans: Most Advantage plans also cover Trelegy, but cost-sharing terms vary.
Tip: Check your Medicare Part D plan’s drug formulary or call your insurer to confirm coverage and exact copay amounts.
2. Manufacturer Programs: None Available
Unlike many inhalers, Trelegy Ellipta does not offer a manufacturer savings card. However, patients with commercial insurance may still receive negotiated copays through their insurer.
No AstraZeneca card support for Trelegy as of 2025.
Medicare enrollees should look into SPAPs (State Pharmaceutical Assistance Programs) or consult with a local benefits counselor for cost support options.
3. Try CIPA-Certified International Pharmacies
Patients paying out-of-pocket can save more than 75% by purchasing through licensed international pharmacies like Planet Drugs Direct or DrugMart, both certified by the Canadian International Pharmacy Association (CIPA). These pharmacies legally ship medications to the U.S. with a valid prescription.
Ready to save up to 70% off your prescription? Purchase from Planet Drugs Direct.
Common Questions
Common questions and answers about Trelegy Ellipta:
1. Is Trelegy Ellipta covered by Medicare?
Yes. Trelegy Ellipta is covered by most Medicare Part D and Medicare Advantage plans. Over 96% of plans list it on their formularies.
2. What will I pay for Trelegy Ellipta with Medicare?
It depends on your plan and your coverage phase. Copays may range from $0 to $100+ per month depending on your deductible and coinsurance.
3. Is there a Trelegy savings card?
No. As of 2025, there is no manufacturer savings card available for Trelegy Ellipta. However, price negotiation through insurance or CIPA-certified pharmacies can offer relief.
4. What if I don’t have insurance?
You can:
Use a CIPA-certified international pharmacy (e.g., $192.99 from Planet Drugs Direct)
Ask your doctor about alternative inhalers
Explore state-based assistance programs or Medicaid if eligible
5. Can my doctor help me get Trelegy covered?
Yes. If you’re on a plan that requires prior authorization, your provider can submit that or write a letter of medical necessity to improve your chances of coverage.
6. How much should I expect to pay for my Trelegy Ellipta prescription over the span of a year?
The annual cost of Trelegy Ellipta depends on your insurance status and where you purchase it:
Without Insurance (U.S. Retail Pharmacies):
Monthly Cost: $802 to $898 per inhaler
Annual Cost (12 months):
Low end: $802 × 12 = $9,624
High end: $898 × 12 = $10,776
Through CIPA-Certified International Pharmacies:
Monthly Cost: As low as $192.99 from Planet Drugs Direct
Annual Cost (12 months):
$192.99 × 12 = $2,315.88
With Medicare Part D or Medicare Advantage
Monthly Cost: Varies by coverage phase (deductible, initial, gap, catastrophic)
Patients typically pay between $0 and $100+ per month
Estimated Annual Cost:
Approximately $600 to $1,200, depending on your plan and prescription tier
Rely on PlanetDrugsDirect.com to Buy Online Trelegy Ellipta
As a trusted prescription referral service, we offer important benefits whenever you order online. Each of our partner pharmacies and/or government-approved dispensaries is committed to providing the best experience possible of any online prescription referral service on the internet. We offer:
Low prices
Quick turn-around times
Generic and brand-name medications
Unparalleled customer service
Sources
U.S. Food and Drug Administration. (2019). Trelegy Ellipta (fluticasone furoate/umeclidinium/vilanterol) [Labeling] (NDAs 209482/S‑003). Retrieved June 2, 2025, from https://www.accessdata.fda.gov/drugsatfda_docs/label/2019/209482s003lbl.pdf
Trelegy®. (n.d.). Savings and support. Retrieved June 2, 2025, from https://www.trelegy.com/savings-and-support/
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