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Eliquis (apixaban) is a prescription oral anticoagulant used to reduce the risk of stroke and blood clots in patients with atrial fibrillation not caused by a heart valve problem. It is also prescribed for treatment and prevention of deep vein thrombosis (DVT) and pulmonary embolism (PE). As a direct factor Xa inhibitor, Eliquis works by preventing clot formation in the blood.

Eliquis is typically taken as a 5mg tablet twice daily, though some patients may be prescribed a lower dose depending on age, kidney function, or body weight. While effective, Eliquis is one of the most expensive blood thinners on the market without insurance. Fortunately, international and discount pharmacies offer substantial savings.

Key Takeaways

U.S. Retail Prices Exceed $600/Month Without Insurance: Major U.S. pharmacies like CVS, Walgreens, and Walmart list branded Eliquis at over $600 for a 30-day supply of 2.5mg, making it one of the costliest anticoagulants available.
International Pharmacies Offer 90–97% Savings: CIPA-certified online pharmacies such as Planet Drugs Direct and DrugMart list generic equivalents of Eliquis for as low as $18.75–$60.57 per 30 tablets (5mg)—a savings of up to $600/month compared to U.S. retail.
Medicare & Manufacturer Savings Help Reduce Out-of-Pocket Costs: Medicare Part D plans often reduce Eliquis copays to $40–$55/month, and manufacturer programs may lower costs to $10 per fill or provide a free 30-day trial for new users. Beginning in 2025, annual out-of-pocket costs under Medicare Part D will be capped at $2,000, further improving affordability.

Cheapest Online Pharmacies for Eliquis (Apixaban) Generic and Generic Equivalents

Here are the cheapest places to get Eliquis (Apixaban) generic and generic equivalents online:

Pharmacy	Prescription Required	30-Tablet Price (Estimated)	Generic Equivalent	Milligram	Website
Planet Drugs Direct	Yes	$18.75	Yes	5mg	Visit
DrugMart	Yes	$60.57	Yes	5mg	Visit
Northwest Pharmacy	Yes	$158.93	No	5mg	Visit
Honeybee Health	Yes	$307.50	Unknown	5mg	Visit
Blink Health (BlinkRx)	Yes	$313.49	No	5mg	Visit

Prices as of April 30, 2025. Prices are subject to change based on quantity, milligram, and other details regarding your prescription needs.

Comparing to Branded Eliquis (Apixaban) Prices in U.S Pharmacies

As of April 30th, 2025, Eliquis (Apixban) is quite expensive in U.S. pharmacies, with average prices seen of (for a 30-day supply):

Pharmacy	30-Day Supply Price	Milligram
Meijer	$603.78	2.5mg
Jewel-Osco	$603.83	2.5mg
Walgreens	$630.10	2.5mg
Walmart	$635.34	2.5mg
CVS Pharmacy	$637.37	2.5mg
Target	$637.37	2.5mg

Prices as of April 30, 2025. Prices are subject to change based on quantity, milligram, pharmacy, available discounts, and more.

Ready to purchase your medication for up to 80% off? Visit Planet Drugs Direct.

Other Ways to Save on Eliquis (Apixaban)

Eliquis is a highly effective but costly blood thinner. Without insurance or discounts, monthly costs can exceed $600 at U.S. pharmacies. Fortunately, there are several strategies to significantly reduce your out-of-pocket expenses:

1. Leverage Your Health Insurance

If you're covered by Medicare Part D or commercial insurance, check your plan’s formulary. Many insurers list Eliquis as a preferred anticoagulant. Using an in-network or preferred pharmacy may further reduce your copay or coinsurance rate.

2. Use Manufacturer Copay Cards or Free Trial Offers

Bristol-Myers Squibb, a manufacturer of Eliquis, offers:

Copay Savings Cards: Eligible commercially insured patients can pay as little as $10 per fill.
Free 30-Day Trial Offers: For first-time users, this can help reduce your initial expense.

You can access these offers through the official Eliquis website.

3. Buy in Bulk (90-Day Supply)

Ask your provider about switching to a 90-day prescription. Many pharmacies and insurers offer discounts on extended fills, reducing your per-tablet cost and minimizing refill trips.

Planet Drugs Direct also offers larger quantities of generic equivalent Eliquis (Apixaban) for up to 80% off (or more) of branded Eliquis. Ready to make a purchase? Go right here.

4. Explore Patient Assistance Programs (PAPs)

If you're uninsured or meet income eligibility requirements, apply to Bristol-Myers Squibb’s Patient Assistance Foundation. Qualifying patients may receive Eliquis at no cost.

For more information visit the official website right here.

5. Shop Around for Prices

Pharmacy pricing can vary widely based on provider and pharmacy:

Use services like SingleCare, GoodRx, or Blink Health to compare pharmacy prices and download discount coupons.
International and CIPA-certified pharmacies can offer up to 80% savings, particularly for generic equivalents and branded Eliquis.

6. Ask About Alternative Medications

In some cases, alternatives like warfarin or generic equivalent apixaban (available internationally) may offer similar clinical benefits at a significantly lower cost. Discuss these options with your healthcare provider if you’re concerned about your upcoming purchase.

7. Government Financial Assistance

Low-income seniors may qualify for the Extra Help program from the Social Security Administration, which can reduce medication costs to as little as $0–$12.15/month. It’s important to cross check these programs with your Medicare coverage (Medicare Part D, in particular).

For more information please visit the Social Security administration website right here.

Common Questions About Saving on Eliquis (Apixaban)

Common questions and answers:

1. Is Eliquis covered by Medicare?

Yes. Eliquis (apixaban) is generally covered by Medicare Part D and many Medicare Advantage (Part C) plans. However, exact coverage, copays, and formulary placement vary by plan. It is not covered under Medicare Part B because it is a prescription drug typically used outside of clinical procedures.

2. How much does Eliquis cost with Medicare?

With Medicare Part D coverage, the average monthly copay for Eliquis ranges from $40 to $55, though some patients may pay less depending on their plan. Eliquis is often listed on Tier 3 of drug formularies, which results in higher copays than Tier 1 or 2 drugs.

3. Does Medicare Part B cover Eliquis?

No. Medicare Part B does not cover Eliquis because it is considered a self-administered outpatient prescription drug. However, it may be covered under Part A (hospital) or Part C (Medicare Advantage) if administered during inpatient care and listed on the plan's formulary.

4. Will Eliquis be cheaper under Medicare in 2025?

Yes. Starting in 2025, Medicare is capping the maximum out-of-pocket cost for all Part D prescriptions at $2,000 per year, down from about $3,300 in 2024. This change could significantly lower total costs for long-term Eliquis users.

5. Are there programs that help reduce the cost of Eliquis?

Yes. Here are several ways to save:

Copay cards from the manufacturer (Bristol-Myers Squibb) can reduce costs for commercially insured patients.
SingleCare and GoodRx offer pharmacy discounts for those without adequate insurance.
Patient Assistance Programs (PAPs) can offer free or reduced-cost Eliquis to eligible low-income individuals.

6. What if my Medicare plan requires prior authorization for Eliquis?

Some Medicare plans require prior authorization or step therapy, meaning you might need to try a lower-cost blood thinner before your plan approves Eliquis. Always review your plan’s drug formulary or speak to your pharmacist or insurer directly to confirm requirements.

Rely on PlanetDrugsDirect.com to Buy Online Eliquis (Apixaban)

As a trusted prescription referral service, we offer important benefits whenever you order online. Each of our partner pharmacies and/or government-approved dispensaries is committed to providing the best experience possible of any online prescription referral service on the internet. We offer:

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Sources

Centers for Medicare & Medicaid Services. (2025). Your guide to Medicare prescription drug coverage (Publication No. 11109). U.S. Department of Health & Human Services. https://www.medicare.gov/publications/11109-your-guide-to-medicare-prescription-drug-coverage.pdf
Bristol-Myers Squibb Company. (2012). ELIQUIS (apixaban) tablets for oral use: Prescribing information. U.S. Food and Drug Administration. https://www.accessdata.fda.gov/drugsatfda_docs/label/2012/202155s000lbl.pdf