Medically reviewed by 
Breztri Aerosphere (Budesonide/Formoterol/Glycopyrronium) is a prescription combination inhaler used in the maintenance treatment of chronic obstructive pulmonary disease (COPD), including chronic bronchitis and emphysema. It combines an inhaled corticosteroid (budesonide), a long-acting beta2-agonist (formoterol), and a long-acting muscarinic antagonist (glycopyrronium) to reduce airway inflammation, improve breathing, and prevent exacerbations.
While clinically proven to improve lung function and reduce flare-ups, Breztri Aerosphere (Budesonide/Formoterol/Glycopyrronium) can be expensive without insurance, costing anywhere from $733 to $823 from most US Pharmacies.
Key Takeaways
CIPA-Certified Online Pharmacies Offer Significant Savings: Verified international pharmacies such as Planet Drugs Direct and DrugMart offer Breztri Aerosphere for as low as $239.99 per inhaler, a savings of more than 65% compared to U.S. pharmacy prices. Purchase from Planet Drugs Direct.
Retail Pharmacies Charge $733 to $823 Without Insurance: U.S. pharmacies including Walgreens, CVS, and Walmart list Breztri Aerosphere between $733 and $823 for a 30-day supply.
Breztri Is Covered by Most Medicare Part D Plans: Coverage is typically included, and some Medicare Advantage plans may also cover it. Copays vary by plan and may not require prior authorization. Manufacturer savings programs and patient support services are also available.
Cheapest Online Pharmacies for Breztri Aerosphere (Budesonide/Formoterol/Glycopyrronium)
Below are the most affordable verified options to purchase Breztri Aerosphere (Budesonide/Formoterol/Glycopyrronium) internationally with a valid prescription:
Pharmacy | Prescription Required | Price (Estimated) | Dosage | Website |
Planet Drugs Direct | Yes | $239.99 | 160mcg/7.2mcg/5mcg per inhalation | |
DrugMart | Yes | $410.20 | 160mcg/7.2mcg/5mcg per inhalation | |
Amazon Pharmacy | Yes | $678.28 | 160mcg/7.2mcg/5mcg per inhalation |
Prices as of June 2, 2025. Pricing may vary based on prescription, location, and dosage.
U.S. Retail Prices for Breztri Aerosphere (Budesonide/Formoterol/Glycopyrronium)
Retail costs for Breztri (Budesonide/Formoterol/Glycopyrronium) remain high across U.S. pharmacies. Below is what you can expect to pay for a 30-day supply without insurance:
Pharmacy | Retail Price |
Meijer Pharmacy | $823.30 |
Aurora Pharmacy | $796.57 |
Mariano’s | $797.50 |
Capsule Pharmacy | $796.57 |
Jewel-Osco | $733.99 |
Walgreens | $799.88 |
Walgreens Specialty Pharmacy | $796.57 |
Walmart | $797.72 |
Walmart Neighborhood Market | $795.27 |
CVS Pharmacy | $785.03 |
Target (CVS) | $785.00 |
Costco | $777.69 |
Retail prices are for one inhaler (30-day supply). Pricing may vary by location and store.
How to Save on Breztri Aerosphere (Budesonide/Formoterol/Glycopyrronium)
Here’s how to save on Breztri Aerosphere (Budesonide/Formoterol/Glycopyrronium):
1. Use Medicare Part D or Medicare Advantage Coverage
Breztri Aerosphere is covered by most Medicare Part D plans. Key details include:
Coverage Status: Generally included in Medicare formularies, meaning it’s accessible for most patients.
Copay Variation: Out-of-pocket costs can vary widely depending on your specific plan, coverage stage, and pharmacy.
Prior Authorization: Often not required, though this may vary by insurer.
Medicare Advantage Plans: Most Medicare Advantage plans with drug coverage also include Breztri.
Tip: Always check your plan’s drug formulary or contact customer service to determine your exact copay and restrictions.
2. Enroll in the Breztri Support Experience
AstraZeneca offers the Breztri Support Experience, which includes:
A Zero Pay Savings Card for eligible commercially insured patients.
How-to resources for inhaler usage.
Newsletters, welcome kits, and education for patients with COPD.
Visit the Breztri Savings & Support Program or call 1-833-458-0440 (Monday–Friday, 8 AM – 8 PM ET).
Note: Savings cards do not apply to patients with Medicare or government-funded insurance, but support services may still be available.
3. Try CIPA-Certified Online Pharmacies
If you’re uninsured or paying cash, ordering through a CIPA-certified pharmacy can reduce your monthly cost from $780+ to as low as $240 per inhaler. These pharmacies are licensed and ship directly to the U.S. with a valid prescription.
Ready to save up to 70% off your prescription? Purchase from Planet Drugs Direct.
Common Questions
Common questions and answers about Breztri Aerosphere (Budesonide/Formoterol/Glycopyrronium):
1. Is Breztri Aerosphere covered by Medicare?
Yes. Most Medicare Part D and Advantage plans cover Breztri Aerosphere. Prior authorization is usually not required, and coverage is more consistent than for many other inhalers.
2. What is the out-of-pocket cost with Medicare?
Your copay will depend on your plan and coverage stage (deductible, initial, gap, or catastrophic). Costs can range from $0 to over $100 depending on your plan.
3. Are there manufacturer programs that help with Breztri?
Yes. AstraZeneca offers the Breztri Zero Pay card for eligible commercial insurance patients. Medicare patients do not qualify for this card but may still benefit from free support resources through the Breztri Support Experience.
4. Can I save money if I don’t have insurance?
Yes. CIPA-certified pharmacies offer major discounts—often over 65% less than U.S. pharmacies. For example, Planet Drugs Direct offers Breztri for $239.99 compared to $780+ at retail.
Rely on PlanetDrugsDirect.com to Buy Online Breztri
As a trusted prescription referral service, we offer important benefits whenever you order online. Each of our partner pharmacies and/or government-approved dispensaries is committed to providing the best experience possible of any online prescription referral service on the internet. We offer:
Low prices
Quick turn-around times
Generic and brand-name medications
Unparalleled customer service
Sources
Breztri® Aerosphere. (n.d.). Savings & support: Patient support. Retrieved June 2, 2025, from https://www.breztri.com/savings-support/patient-support
U.S. Food and Drug Administration. (2020). Breztri Aerosphere (budesonide/glycopyrrolate/formoterol fumarate) [Labeling] (NDAs 212122/S‑000). Retrieved June 2, 2025, from https://www.accessdata.fda.gov/drugsatfda_docs/label/2020/212122s000lbl.pdf
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