Medically reviewed by 
NUBEQA (darolutamide) is a prescription oral medication used to treat prostate cancer, including non-metastatic castration-resistant prostate cancer (nmCRPC) and metastatic hormone-sensitive prostate cancer (mHSPC). It works by blocking androgen receptors to slow the growth of prostate cancer cells. NUBEQA is typically taken as 600 mg (two 300 mg tablets) twice daily with food.
Without insurance, NUBEQA (darolutamide) can be expensive, with U.S. retail prices exceeding $3,600 for a 30-day supply.
Key Takeaways
Online Pharmacies Offer Substantial Savings: CIPA-certified international pharmacies like DrugMart and Planet Drugs Direct list NUBEQA (darolutamide) at approximately $938 for a 30-day supply when purchased in bulk—saving up to 65% compared to U.S. pharmacies. Purchase from Planet Drugs Direct.
U.S. Pharmacies Charge $3,550–$3,641 Monthly Without Insurance: Retail pharmacies like Walgreens and CVS price NUBEQA at over $3,500 for 30 tablets.
NUBEQA Is Covered by Medicare and Commercial Insurance: Coverage under Medicare Part D and private plans is available, though prior authorization is often required.
Copay Assistance May Reduce Costs to $0: Eligible commercially insured patients may pay as little as $0 through the Bayer NUBEQA Copay Program, which offers up to $25,000 in annual savings.
Cheapest Online Pharmacies for NUBEQA (Darolutamide)
Here are the cheapest places to purchase NUBEQA (Darolutamide) online:
Pharmacy | Prescription Required | Price (30 Tablets) | Dosage | Website |
Blink Health | Yes | $3,550.11 | 300mg | |
Planet Drugs Direct | Yes | ~$938 (prorated) | 300mg | |
DrugMart | Yes | ~$938 (prorated) | 300mg |
Prices as of July 1, 2025. Note: DrugMart and Planet Drugs Direct prices are based on 336-tablet bulk packages priced at $10,506.96 and $10,506.99 respectively (approximately 11-month supply).
U.S. Retail Pharmacy Prices for NUBEQA
U.S. retail pharmacy prices for NUBEQA (Darolutamide):
Pharmacy | Retail Price (30 Tablets) | Price per Tablet |
Walgreens | $3,561.92 | $118.73 |
CVS | $3,641.80 | $121.39 |
CVS inside Target | $3,641.80 | $121.39 |
Prices are current as of July 1 2025, and may vary by location.
How to Save on NUBEQA (Darolutamide)
Here’s how to save on NUBEQA (Darolutamide):
1. Use Medicare Part D or Commercial Insurance
NUBEQA is typically covered under Medicare Part D and commercial insurance plans. However, it is often placed on a specialty tier (e.g., Tier 5), requiring prior authorization and high out-of-pocket costs depending on the benefit phase.
2. NUBEQA Copay Card Program
The Bayer NUBEQA $0 Copay Program helps reduce out-of-pocket costs for eligible patients with commercial insurance:
Pay as little as $0 per fill
Save up to $25,000 annually
Not valid for patients enrolled in federal or state healthcare programs (Medicare, Medicaid, etc.)
Cannot be combined with other benefit programs
To learn more or enroll, click here.
3. Access Services by Bayer
Patients can contact Access Services by Bayer at 1-800-288-8374 to receive support with:
Copay assistance
Prior authorization and appeals
Understanding insurance coverage
Referrals to additional financial assistance
4. CIPA-Certified International Pharmacies
Licensed international pharmacies can reduce costs by more than 60%. A valid prescription is required, and medications are shipped from regulated pharmacies in Canada or other countries.
Save up to 80% off your prescription by using Planet Drugs Direct. Ready to purchase? Purchase from Planet Drugs Direct.
Medicare Coverage and Cost Considerations
NUBEQA is generally covered under Medicare Part D, though costs and requirements vary:
Prior Authorization: Some plans may require approval before dispensing.
Cost Sharing: Even with coverage, patients may be responsible for deductibles, coinsurance, or copays.
Payment Planning: The Medicare Prescription Payment Plan allows beneficiaries to spread out costs monthly.
Appeals Process: Approximately 60% of denied NUBEQA prior authorizations are approved upon appeal, according to manufacturer data.
Annual Cost Comparison for NUBEQA (Darolutamide)
Based on where you purchase your annual cost for prescriptions may drastically vary:
Purchase Method | Monthly Estimate | Annual Estimate |
U.S. Retail Pharmacy | $3,550 – $3,641 | $42,600 – $43,700 |
CIPA Online Pharmacy (bulk) | ~$938 (prorated) | ~$11,250 |
Medicare Part D (2025 cap) | Max $2,000/year | $2,000 |
Bayer Copay Card (Commercial) | As low as $0/month | Varies (max $25,000) |
Common Questions About NUBEQA (Darolutamide)
Common questions and answers about NUBEQA (Darolutamide):
Is NUBEQA covered by Medicare?
Yes. NUBEQA is typically covered under Medicare Part D, though prior authorization is often required. Patients may face out-of-pocket costs depending on their coverage phase.
How can I save on NUBEQA without insurance?
Patients without insurance may benefit from ordering through licensed international pharmacies, which offer bulk pricing significantly below U.S. retail rates.
Who qualifies for the NUBEQA copay card?
Only patients with commercial insurance are eligible. Individuals with Medicare, Medicaid, or other government-funded coverage are not eligible.
How do I appeal a denied NUBEQA prescription under Medicare?
Your healthcare provider can initiate an appeal. However, according to Bayer, approximately 60% of appeals for NUBEQA prior authorization are successful.
Rely on PlanetDrugsDirect.com to Buy Online Prescription Nubeqa
As a trusted prescription referral service, we offer important benefits whenever you order online. Each of our partner pharmacies and/or government-approved dispensaries is committed to providing the best experience possible of any online prescription referral service on the internet. We offer:
Low prices
Quick turn-around times
Generic and brand-name medications
Unparalleled customer service
Sources
U.S. Food and Drug Administration. NUBEQA (darolutamide) Prescribing Information. 2022, https://www.accessdata.fda.gov/drugsatfda_docs/label/2022/212099s002lbl.pdf. Accessed 1 July 2025.
Bayer HealthCare Pharmaceuticals Inc. NUBEQA® $0 Co‑Pay Card. NUBEQA US, https://www.nubeqa-us.com/savings-support/nubeqa-copay-card. Accessed 1 July 2025.
Related Articles
Treatment of Benign Prostatic Hypertrophy in a 64-Year-Old Man Using Dutasteride
Author’s Note: H.I. was a long-time patient of mine. I typically manage my patients in-office before referring them to specialists. However, in this case, due to...
Colorado Seeking To Join Florida In Importing Prescription Drugs From Canada
As prescription drug costs have risen over the years, so have concerns related to the impact. These prices aren’t just affecting bank accounts, they’re affecting...
Erectile dysfunction (ED) is one of the most prevalent sexual debilitation. About 20 percent of all men suffer from ED at one time or another, and...
